Publications

Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.

2024

Syyskuu

The association of common autoimmune diseases with autoimmune thyroiditis: a two-sample Mendelian randomization study

Zhang K, Luo Z, Wang X.

Front Endocrinol (Lausanne). 2024 Sep 9;15:1383221. doi: 10.3389/fendo.2024.1383221.

Role of the X Chromosome in Alzheimer Disease Genetics

Belloy ME, Le Guen Y, Stewart I, Williams K, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD.

JAMA Neurol. 2024 Oct 1;81(10):1032-1042. doi: 10.1001/jamaneurol.2024.2843.

Role of the X Chromosome in Alzheimer Disease Genetics

Belloy ME, Le Guen Y, Stewart I, Williams K, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD. Role of the X Chromosome in Alzheimer Disease Genetics.

JAMA Neurol. 2024 Oct 1;81(10):1032-1042. doi: 10.1001/jamaneurol.2024.2843.

Genetic estimation of causalities between educational attainment with common digestive tract diseases and the mediating pathways

Wang Y, Bi Y, Wang Y, Ji F, Zhang L.

BMC Gastroenterol. 2024 Sep 9;24(1):304. doi: 10.1186/s12876-024-03400-x.

From proteome to pathogenesis: investigating polycystic ovary syndrome with Mendelian randomization analysis

Zhang J, Li Y, Gong A, Wang J.

Front Endocrinol (Lausanne). 2024 Sep 9;15:1442483. doi: 10.3389/fendo.2024.1442483.

The causal relationship between CSF metabolites and GBM: a two-sample mendelian randomization analysis

Bao H, Chen Y, Meng Z, Chu Z.

BMC Cancer. 2024 Sep 9;24(1):1119. doi: 10.1186/s12885-024-12901-7.

Causal Relationships between Gut Microbiotas, Blood Metabolites, and Neuroendocrine Tumors: A Mediated Mendelian Randomization Study

Cao Z, Huang J, Long X.

Neuroendocrinology. 2024 Sep 9:1-12. doi: 10.1159/000541298.

Exploring the mechanisms and relationship between body mass index and asthma: findings from Mendelian randomization

Yang Y, Wang X, Yang W.

J Asthma. 2024 Sep 7:1-13. doi: 10.1080/02770903.2024.2400279.

Gut microbiota and risk of ankylosing spondylitis

Jiang X, Wang M, Liu B, Yang H, Ren J, Chen S, Ye D, Yang S, Mao Y.

Clin Rheumatol. 2024 Nov;43(11):3351-3360. doi: 10.1007/s10067-024-07102-3.

Causal relationship between systemic circulatory inflammatory regulators and intervertebral disc degeneration: A bidirectional 2-sample Mendelian randomization study

Chen ZX, Xu B, Huang ZL, Liu YJ, Li YW, Lu BJ, Lin J, Zhang XD, Shen XF.

Medicine (Baltimore). 2024 Sep 6;103(36):e39521. doi: 10.1097/MD.0000000000039521.

Causal Relationships Between Retinal Diseases and Psychiatric Disorders Have Implications for Precision Psychiatry

Zhang Z, Bao S, Yan D, Zhai M, Qu J, Zhou M.

Mol Neurobiol. 2024 Sep 6. doi: 10.1007/s12035-024-04456-2.

Proteome-wide mendelian randomization identifies therapeutic targets for nephrolithiasis

Wang L, Li KP, Chen SY, Wan S, Li XR, Yang L.

Urolithiasis. 2024 Sep 6;52(1):126. doi: 10.1007/s00240-024-01627-7.

Impact of 26 Skin Diseases on the Risk of Non-Small Cell Lung Cancer: A Mendelian Randomization Study Using FinnGen R11 Data

Li X, Li H.

medRxiv 2024.09.05.24313092; doi: https://doi.org/10.1101/2024.09.05.24313092

Research on the causal relationship between fine particulate matter and type 2 diabetes mellitus: A two-sample multivariable mendelian randomization study

Shou X, Yao Z, Wang Y, Chai Y, Huang Y, Chen R, Gu W, Liu Q.

Nutr Metab Cardiovasc Dis. 2024 Sep 5:S0939-4753(24)00332-6. doi: 10.1016/j.numecd.2024.08.023.

Association of autoimmune diseases with the occurrence of osteoarthritis: a gene expression and Mendelian randomization study

Dan J, Lu HM, Zhou X, Wang HY, Wang JH.

Front Med (Lausanne). 2024 Sep 5;11:1435312. doi: 10.3389/fmed.2024.1435312.

Bias from heritable confounding in Mendelian randomization studies

Sanderson E, Rosoff D, Palmer T, Tilling K, Smith GD, Hemani G.

medRxiv 2024.09.05.24312293; doi: https://doi.org/10.1101/2024.09.05.24312293

Causal relationship between circulating immune cells and gastric cancer: a bidirectional Mendelian randomization analysis using UK Biobank and FinnGen datasets

Yang W, Ou Y, Luo H, You L, Du H.

Transl Cancer Res. 2024 Sep 30;13(9):4702-4713. doi: 10.21037/tcr-24-480.

Integration of GWAS and multi-omic QTLs identifies uncharacterized COVID-19 gene-biotype and phenotype associations

Oliva M, King E, Hammond R, Lee JS, Riley-Gillis B, Resztak J, Degner J.

medRxiv 2024.09.05.24313137; doi: https://doi.org/10.1101/2024.09.05.24313137

Immune Cell Influence on Diffuse Large B-Cell Lymphoma: A Mendelian Randomization Analysis

He H, Zhong J, Li Q, Deng C, Yuan X, Zhang K, Nie L, Cai N.

bioRxiv 2024.09.05.611435; doi: https://doi.org/10.1101/2024.09.05.611435

Exploring the causal link among statin drugs and the osteoarthritis risk based on Mendelian randomization research

Chen W, Sun Z, Xiong X, Tan H, Hu J, Liu C, Chen C.

Front Genet. 2024 Sep 4;15:1390387. doi: 10.3389/fgene.2024.1390387.

Causation between the gut microbiota and inguinal hernia: a two-sample double-sided Mendelian randomization study

Wu C, Zhu Y, Xi H.

Sci Rep. 2024 Sep 4;14(1):20526. doi: 10.1038/s41598-024-71253-1.

Causal effects of obstructive sleep apnea on chronic kidney disease and renal function: a bidirectional Mendelian randomization study

Hou Y, Li Y, Xiao Z, Wang Z.

Front Neurol. 2024 Sep 4;15:1323928. doi: 10.3389/fneur.2024.1323928.

Leveraging pleiotropy identifies common-variant associations with selective IgA deficiency

Willis TW, Gkrania-Klotsas E, Wareham NJ, McKinney EF, Lyons PA, Smith KGC, Wallace C.

Clin Immunol. 2024 Nov;268:110356. doi: 10.1016/j.clim.2024.110356.

Causal Relationship Between Autoimmune Arthritis and Temporomandibular Disorders

Li XF, Cai JW, Hu YY, Niu YM.

Int Dent J. 2024 Sep 3:S0020-6539(24)01417-5. doi: 10.1016/j.identj.2024.08.006.

Metabolic Characteristics of Gut Microbiota and Insomnia: Evidence from a Mendelian Randomization Analysis

Xie F, Feng Z, Xu B.

Nutrients. 2024 Sep 2;16(17):2943. doi: 10.3390/nu16172943.

The causal association between gut microbiota and postpartum depression: a two-sample Mendelian randomization study

Jin W, Li B, Wang L, Zhu L, Chai S, Hou R.

Front Microbiol. 2024 Sep 2;15:1415237. doi: 10.3389/fmicb.2024.1415237.

Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset

von Berg J, McArdle PF, Häppölä P, Haessler J, Kooperberg C, Lemmens R, Pezzini A, Thijs V, Pulit SL, Kittner SJ, Mitchell BD, de Ridder J, van der Laan SW.

Front Genet. 2024 Sep 2;15:1392061. doi: 10.3389/fgene.2024.1392061.

Lipids, lipid-lowering drugs and lateral epicondylitis of the humerus: a drug-targeted Mendelian randomization study

Liu MM, Chen X, Bao XH, Huang BH.

Front Genet. 2024 Sep 2;15:1437712. doi: 10.3389/fgene.2024.1437712.

Effects of rheumatoid arthritis on ventricular structure and function: a Mendelian randomization study

Hao Liu, Di Luo, Wei Yan, Jinsong Li, Dezhi Yan

Researchsquare, 02 September 2024, doi: 10.21203/rs.3.rs-4713343/v1

Association of maternal gut microbial metabolites with gestational diabetes mellitus: evidence from an original case-control study, meta-analysis, and Mendelian randomization

Yao M, Xiao Y, Sun Y, Zhang B, Ding Y, Ma Q, Liang F, Yang Z, Ge W, Liu S, Xin L, Yin J, Zhu X.

Eur J Clin Nutr. 2024 Sep 2. doi: 10.1038/s41430-024-01502-z.

Causal associations between gut microbiota and premature rupture of membranes: a two-sample Mendelian randomization study

Zhang L, Li Q, Huang J, Zou Q, Zou H, Zhang X, Su Y, Li C.

Front Immunol. 2024 Sep 2;15:1440232. doi: 10.3389/fimmu.2024.1440232.

Polygenic risk score portability for common diseases across genetically diverse populations

Moreno-Grau S, Vernekar M, Lopez-Pineda A, Mas-Montserrat D, Barrabés M, Quinto-Cortés CD, Moatamed B, Lee MTM, Yu Z, Numakura K, Matsuda Y, Wall JD, Ioannidis AG, Katsanis N, Takano T, Bustamante CD.

Hum Genomics. 2024 Sep 2;18(1):93. doi: 10.1186/s40246-024-00664-y.

Association of gut microbiota with acute kidney injury: a two-sample Mendelian randomisation and case-control study

Liu Y, Zhang J, Zhou Y, Xin Y, Li H, Huang P, Li N, Zhou Y, Luan F, Li Y, Zhang Q, Yuan M, Liu Y, Liu L, Song Y, Shen L, Xiao Y, Liu Y, Peng Y, Wang X, Yu K, Zhao M, Wang C.

Benef Microbes. 2024 Sep 2:1-15. doi: 10.1163/18762891-bja00032.

Whole -genome survival analysis of 144 286 people from the UK Biobank identifies novel loci associated with blood pressure

Saluja S, Darlay R, Lennon R, Keavney BD, Cordell HJ.

J Hypertens. 2024 Sep 1;42(9):1647-1652. doi: 10.1097/HJH.0000000000003801.

Risk of Parkinson's disease and depression severity in different populations: A two-sample Mendelian randomization analysis

Qin Y, Li J, Quan W, Song J, Xu J, Chen J.

Brain Behav. 2024 Sep;14(9):e3642. doi: 10.1002/brb3.3642.

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Parkinson's disease and the risk of gastrointestinal cancers: a two-sample Mendelian randomization study

Liu Z, Cui L.

J Gastrointest Oncol. 2024 Aug 31;15(4):1475-1486. doi: 10.21037/jgo-24-106.

Elucidating the causal nexus between antibody-mediated immunity and autoimmune diseases: Insights from bidirectional mendelian randomization, gene expression profiling, and drug sensitivity analysis

Chen J, Wei C, Huang S, Wu S, He R, Chen T, Qin X, Wei W, Qin B, Wu S, Zhu J, Huang C, Feng S, Zhou Z, Zhang B, Xue J, Mo S, Zhou C, Qin Y, Zhan X, Liu C.

Int Immunopharmacol. 2024 Aug 30;142(Pt A):113027. doi: 10.1016/j.intimp.2024.113027.

Specific blood metabolite associations with Gout: a Mendelian randomization study

Zeng H, Lai J, Liu Z, Liu W, Zhang Y.

Eur J Clin Nutr. 2024 Aug 30. doi: 10.1038/s41430-024-01497-7.

Health condition and socioeconomic status mediate the causal effect of reproductive traits on nonalcoholic fatty liver disease: evidence from Mendelian randomization study

Wang Q, Wang L, Hao R, Zhang L, Wang W, Xia L.

Front Endocrinol (Lausanne). 2024 Aug 30;15:1419964. doi: 10.3389/fendo.2024.1419964.

Causal Effects of Kidney Function and Chronic Kidney Disease on Alzheimer's Disease by Analyzing Large-Scale Genome-Wide Association Study Datasets

Zhao H, Yuan H, Wang E.

J Alzheimers Dis. 2024 Aug 30. doi: 10.3233/JAD-240807.

Mitochondrial dysfunction and onset of type 2 diabetes along with its complications: a multi-omics Mendelian randomization and colocalization study

Li Y, Miao Y, Feng Q, Zhu W, Chen Y, Kang Q, Wang Z, Lu F, Zhang Q.