Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.
2024

Elokuu

Causal association of type 2 diabetes with central retinal artery occlusion: a Mendelian randomization study
Liu T, Lu Q, Liu Z, Lin X, Peng L, Lu X, Guo W, Liu P, Zhang N, Wu S.
Front Endocrinol (Lausanne). 2024 Aug 8;15:1379549. doi: 10.3389/fendo.2024.1379549.
Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations
Argentieri MA, Xiao S, Bennett D, Winchester L, Nevado-Holgado AJ, Ghose U, Albukhari A, Yao P, Mazidi M, Lv J, Millwood I, Fry H, Rodosthenous RS, Partanen J, Zheng Z, Kurki M, Daly MJ, Palotie A, Adams CJ, Li L, Clarke R, Amin N, Chen Z, van Duijn CM.
Nat Med. 2024 Sep;30(9):2450-2460. doi: 10.1038/s41591-024-03164-7.
Platelet indices and the risk of pulmonary arterial hypertension: a two-sample and multivariable Mendelian randomization study
Li Y, Liu X, Hong Q, Xu R.
Front Cardiovasc Med. 2024 Aug 8;11:1395245. doi: 10.3389/fcvm.2024.1395245.
Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media
Bizaki-Vallaskangas A, Rämö J, Sliz E, Kivekäs I, Willberg T, Saarentaus E, Toppila-Salmi S, Dietz A, Haapaniemi T, Hytönen VP, Toivola S, Palotie A, Mäkitie A, Kettunen J.
Sci Rep. 2024 Aug 7;14(1):18344. doi: 10.1038/s41598-024-68781-1.
Central corneal thickness and the risk of primary open-angle glaucoma: a Mendelian randomisation mediation analysis
Katsimpris A, Baumeister SE, Baurecht H, Tatham AJ, Nolde M.
Br J Ophthalmol. 2024 Aug 7:bjo-2023-324996. doi: 10.1136/bjo-2023-324996..
Polyunsaturated fatty acids and diabetic microvascular complications: a Mendelian randomization study
Liu B, Liu R, Gu Y, Shen X, Zhou J, Luo C.
Front Endocrinol (Lausanne). 2024 Aug 7;15:1406382. doi: 10.3389/fendo.2024.1406382.
25-Hydroxyvitamin D, Vitamin D Binding Protein and Gestational Diabetes Mellitus: A Two-Sample Mendelian Randomization Study
Qiu Y, Ainiwan D, Huang Y, Zhang L, Cheng H, Alifu X, Zhou H, Xv N, Wang B, Wang S, Chen Z, Liu H, Chen D, Yu Y.
Nutrients. 2024 Aug 7;16(16):2603. doi: 10.3390/nu16162603.
Potential Causal Relationship between Faster Walking Pace and Reduced Migraine Risk: A Mendelian Randomization Study
Liu X, Zhang J.
medRxiv 2024.08.07.24311600; doi: https://doi.org/10.1101/2024.08.07.24311600
Circulating inflammatory cytokines and the risk of sepsis: a bidirectional mendelian randomization analysis
Jiang WX, Li HH.
BMC Infect Dis. 2024 Aug 7;24(1):793. doi: 10.1186/s12879-024-09689-z.
Fast and scalable ensemble learning method for versatile polygenic risk prediction
Chen T, Zhang H, Mazumder R, Lin X.
Proc Natl Acad Sci U S A. 2024 Aug 13;121(33):e2403210121. doi: 10.1073/pnas.2403210121.
Associations of genetically predicted iron status with 24 gastrointestinal diseases and gut microbiota: a Mendelian randomization study
Su T, Peng X, Gan Y, Wu H, Ma S, Zhi M, Lu Y, Dai S, Yao J.
Front Genet. 2024 Aug 7;15:1406230. doi: 10.3389/fgene.2024.1406230.
Fast and scalable ensemble learning method for versatile polygenic risk prediction
Chen T, Zhang H, Mazumder R, Lin X.
Proc Natl Acad Sci U S A. 2024 Aug 13;121(33):e2403210121. doi: 10.1073/pnas.2403210121.
Multisystem health comorbidity networks of metabolic dysfunction-associated steatotic liver disease
Jiang F, Wang L, Ying H, Sun J, Zhao J, Lu Y, Bian Z, Chen J, Fang A, Zhang X, Larsson SC, Mantzoros CS, Wang W, Yuan S, Ding Y, Li X.
Med. 2024 Aug 6:S2666-6340(24)00295-2. doi: 10.1016/j.medj.2024.07.013.
No Causal Relationship Between Coagulation Factors and Sepsis-Related Risks: A Mendelian Randomization Study
Jingchao Lei, Jing Qi, Jia Zhai, Yao Zhang, Chuanzheng Sun
Researchsquare, 06 August 2024, doi: 10.21203/rs.3.rs-4727406/v1
Mendelian randomization based on immune cells in diabetic nephropathy
Zhou Y, Zhang H, Yan H, Huang C, Liu Y.
Front Endocrinol (Lausanne). 2024 Aug 6;15:1460652. doi: 10.3389/fendo.2024.1460652.
The association between immune cells and epilepsy：Evidence from Mendelian randomization study and meta-analysis
Xiangyi Wang, Shenggen Chen, Man Li, Luyan Wu, Yuying Zhang, 婉挥 Lin, Chaofeng Zhu, Huapin Huang
Researchsquare, 06 August 2024, doi:10.21203/rs.3.rs-4697272/v1
Whole-exome and whole-genome sequencing of 1064 individuals with type 1 diabetes reveals novel genes for diabetic kidney disease
Haukka JK, Antikainen AA, Valo E, Syreeni A, Dahlström EH, Lin BM, Franceschini N, Krolewski AS, Harjutsalo V, Groop PH, Sandholm N; FinnDiane Study Group.
Diabetologia. 2024 Aug 6. doi: 10.1007/s00125-024-06241-1.
Revealing the link between gut microbiota and brain tumor risk: a new perspective from Mendelian randomization
Yang J, Lu J, Dong Y, Wei Y, Christian M, Huang J, Kuang H, Cao D.
Front Cell Infect Microbiol. 2024 Aug 6;14:1404745. doi: 10.3389/fcimb.2024.1404745.
Exploring the causality of appendectomy and ischaemic heart disease: a Mendelian randomization study and meta-analysis
Wang S, Zhang T, Sun Y, Yao Y, Yang D, Cao X.
Front Cardiovasc Med. 2024 Aug 6;11:1443906. doi: 10.3389/fcvm.2024.1443906.
Causal relationships of infection with Helicobacter pylori and herpesvirus on periodontitis: A Mendelian randomization study
Wu E, Cheng M, Yang S, Yuan W, Gu M, Lu D, Zhang L, Wang Q, Sun X, Shao W.
Heliyon. 2024 Aug 6;10(16):e35904. doi: 10.1016/j.heliyon.2024.e35904.
Genetic association of lipid and lipid-lowering drug target genes with atopic dermatitis: a drug target Mendelian randomization study
Niu Q, Zhang T, Mao R, Zhao N, Deng S.
Sci Rep. 2024 Aug 5;14(1):18097. doi: 10.1038/s41598-024-69180-2.
Bidirectional two-sample Mendelian randomization analysis identifies causal associations between migraine and five psychiatric disorders
Li WW, Zhang JX, Wang J, Chen YQ, Lai S, Qiu ZK.
Front Neurol. 2024 Aug 5;15:1432966. doi: 10.3389/fneur.2024.1432966.
Relationship between circulating white blood cell count and inflammatory skin disease: a bidirectional mendelian randomization study
Yuan J, Che Y, Wang Q, Xiao Q.
Arch Dermatol Res. 2024 Aug 5;316(8):504. doi: 10.1007/s00403-024-03241-4.
Causal association between Helicobacter pylori infection and Sjogren's syndrome: a bidirectional Mendelian randomization analysis
Cui D, An R, Li L, Jiang L, Jiang C, Jin J.
BMC Infect Dis. 2024 Aug 5;24(1):782. doi: 10.1186/s12879-024-09678-2.
Mendelian randomization analysis identified potential genes pleiotropically associated with gout
Wang Y, Chen J, Yao H, Li Y, Xu X, Zhang D.
Front Genet. 2024 Aug 5;15:1426860. doi: 10.3389/fgene.2024.1426860.
Perspective Exploring Novel Associations of IL-18 Levels as a Mediator of the Causal Links between Major Depression and Reproductive Health
Li M, Sun K, Mei Y, Liu K, Chen L, Guo Y.
Depress Anxiety. 2024 Aug 5;2024:9234876. doi: 10.1155/2024/9234876.
Association between Kidney Stones and CKD: A Bidirectional Mendelian Randomization Study
Zhou LT, Ali AE, Jayachandran M, Haskic Z, Harris PC, Rule AD, Koo K, McDonnell SK, Larson NB, Lieske JC.
J Am Soc Nephrol. 2024 Aug 5. doi: 10.1681/ASN.0000000000000453.
Causal roles of skin microbiota in skin cancers suggested by genetic study
Zhu Y, Liu W, Wang M, Wang X, Wang S.
Front Microbiol. 2024 Aug 5;15:1426807. doi: 10.3389/fmicb.2024.1426807.
Causal relationship between gut microbiota and vulvar cancer: a two-sample bi-directional Mendelian randomization study
Chen J, Wang P, Xiao C, Kelaimu K, Zeng Y, Lyu F, Gao X, Li X, Hu J.
medRxiv 2024.08.04.24311470; doi: https://doi.org/10.1101/2024.08.04.24311470
Causal role of immune cells in aplastic anemia: Mendelian randomization (MR) study
Fu S, Du Y, Pan T, Ma F, He H, Li Y.
Sci Rep. 2024 Aug 3;14(1):18010. doi: 10.1038/s41598-024-69104-0.
Mendelian randomization demonstrates a causal link between peripheral circulating acylcarnitines and intracranial aneurysms
Wang Y, Xie K, Wang J, Chen F, Li X, Zhang L.
Neurotherapeutics. 2024 Aug 3:e00428. doi: 10.1016/j.neurot.2024.e00428.
Exploring the Association Between Gastroesophageal Reflux and Temporomandibular Joint Disorder in European Populations: A Bidirectional Mendelian Randomization Analysis
Gu R, Chen L, Hua M, Miao H, Qin Y.
Int Dent J. 2024 Aug 3:S0020-6539(24)01401-1. doi: 10.1016/j.identj.2024.07.1210.
Genetically Proxied Appendicular Lean Mass and Stroke Risk:a Two-step Mendelian Randomization Study
Li Z, Liu X, Wen J, Wang Z, Xie Y, Zhu L, Wu X, Fang C, Tian Y, Li Q.
J Stroke Cerebrovasc Dis. 2024 Aug 2:107915. doi: 10.1016/j.jstrokecerebrovasdis.2024.107915.
Immune thrombocytopenia increases the risk of thrombosis: A two-sample Mendelian randomization study
Yu J, Fu L, Jin G, Gao F, Ding L, Hong L, Lv S, Jin J, Tang L, Feng W, Zhang K, Xu C.
Int J Cardiol. 2024 Aug 2:132417. doi: 10.1016/j.ijcard.2024.132417.
Senescence-related genes and proteins in the development of Alzheimer's disease: evidence from transcriptomic and Mendelian randomization analysis
Liu Y, Chen J.
Front Aging Neurosci. 2024 Aug 2;16:1423725.
Association between gut microbiota and diabetic microvascular complications: a two-sample Mendelian randomization study
Zhou P, Hao Z, Chen Y, Zhang Z, Xu W, Yu J.
Front Endocrinol (Lausanne). 2024 Aug 2;15:1364280. doi: 10.3389/fendo.2024.1364280.
Causal effects of gut microbiota on diabetic neuropathy: a two-sample Mendelian randomization study
Xu M, Hao J, Qi Y, Wu B, Li R, Yang X, Zhang Y, Liu Y.
Front Endocrinol (Lausanne). 2024 Aug 2;15:1388927. doi: 10.3389/fendo.2024.1388927.
Exploring the causal relationships between cholelithiasis, cholecystitis, cholecystectomy, and gastroesophageal reflux disease: A bidirectional two-sample mendelian randomization study
Lin H, Lu R, Shang Q, Gu Y, Liu Y, Yang Y, Chen L.
Int J Surg. 2024 Aug 2. doi: 10.1097/JS9.0000000000001992.
Causal effects of endometriosis stages and locations on menstruation, ovulation, reproductive function, and delivery modes: a two-sample Mendelian randomization study
Shen L, Li J, Zhang H, Zhao Y.
Front Endocrinol (Lausanne). 2024 Aug 2;15:1328403. doi: 10.3389/fendo.2024.1328403.
The Causal Effect of Serum Lipid Levels Mediated by Neuregulin 4 on the Risk of Four Atherosclerosis Subtypes: Evidence from Mendelian Randomization Analysis
Zheng L, Zhang C, Bu S, Guo W, Li T, Xu Y, Liu Y, Yuan C, Feng C, Zong G, Zhu J, Xing M, Geng X.
Vasc Health Risk Manag. 2024 Aug 1;20:351-357. doi: 10.2147/VHRM.S459075.
Statins inhibit paclitaxel-induced PD-L1 expression and increase CD8+ T cytotoxicity for better prognosis in breast cancer
Li L, Wang H, Zhang S, Gao S, Lu X, Pan Y, Tang W, Huang R, Qiao K, Ning S.
Int J Surg. 2024 Aug 1;110(8):4716-4726. doi: 10.1097/JS9.0000000000001582.
The Causal Effects between Mood Swings and Gastrointestinal Diseases: A Mendelian Randomization Study
Wang K, Wang S, Chen X.
Alpha Psychiatry. 2024 Aug 1;25(4):533-540. doi: 10.5152/alphapsychiatry.2024.241688.
Exploring the causal effect between lipid-modifying drugs and idiopathic pulmonary fibrosis: a drug-target Mendelian randomization study
Gexiang Cai, Jingjing Liu, Mengsi Cai, Lianyou Shao
Lipids Health Dis . 2024 Aug 1;23(1):237. doi: 10.1186/s12944-024-02218-6.
Gastroesophageal reflux disease increases the risk of rheumatoid arthritis: a bidirectional two-sample Mendelian randomization study
Yuan Q, Shen Z, Zhang J, Liu Q, Whang H, Li Y.
Sci Rep. 2024 Aug 1;14(1):17796. doi: 10.1038/s41598-024-64966-w.
Effect of trace elements and nutrients on diabetes and its complications: a Mendelian randomization study
Jia MJ, Chen L.
Front Nutr. 2024 Aug 1;11:1439217. doi: 10.3389/fnut.2024.1439217.
Elucidating the role of genetically determined metabolites in Diabetic Retinopathy: insights from a mendelian randomization analysis
Tan Y, Yan Z, Yin J, Cao J, Xie B, Zhang F, Zhang W, Xiong W.
Acta Diabetol. 2024 Aug 1. doi: 10.1007/s00592-024-02345-7.
Causal relationship between air pollution and infections: a two-sample Mendelian randomization study
Yang S, Tong T, Wang H, Li Z, Wang M, Ni K.
Front Public Health. 2024 Aug 1;12:1409640. doi: 10.3389/fpubh.2024.1409640.
Exploring the causal effect between lipid-modifying drugs and idiopathic pulmonary fibrosis: a drug-target Mendelian randomization study
Cai G, Liu J, Cai M, Shao L.
Lipids Health Dis. 2024 Aug 1;23(1):237. doi: 10.1186/s12944-024-02218-6.
Periodontitis and Chronic Obstructive Pulmonary Disease: A bidirectional Mendelian randomization study
Chen M, Chang S, Xu Y, Zhang L, Guo H, Liu J.
Community Dent Health. 2024 Aug 30;41(3):177-182. doi: 10.1922/CDH_00036Chen06.

Heinäkuu

Mendelian randomization study of inflammatory bowel disease and type 1 diabetes
Zhu JY, Ma X, Liu MY, Ma LZ, Sun XR, Yan MY, Xue C, Sun C.
Endocrine. 2024 Jul 31. doi: 10.1007/s12020-024-03919-9.