Publications

Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.

2024

Elokuu

The Causal Relationship Between Physical Activity and Skin Cancer Risk: An Univariable Mendelian Randomization Study

Fu X, Zeng F, Li L, Liu G, Zhong Q, Chen S.

Clin Cosmet Investig Dermatol. 2024 Aug 28;17:1963-1972. doi: 10.2147/CCID.S472443.

Quantifying variant contributions in cystic kidney disease using national-scale whole genome sequencing

Sadeghi-Alavijeh O, Chan MM, Doctor GT, Voinescu CD, Stuckey A, Kousathanas A, Ho AT, Stanescu HC, Bockenhauer D, Sandford RN, Levine AP, Gale DP.

J Clin Invest. 2024 Aug 27:e181467. doi: 10.1172/JCI181467.

Multivariable Mendelian Randomization Analysis Reveals the Protective Effect of Restless Legs Syndrome against Lower Limb Venous Diseases and Pulmonary Embolism

Zhang R-Y, Wen C, Geng R-L, Su J-H, Liu X-H, Lai Z-Y, Tao E-X, Li F-J.

medRxiv 2024.08.27.24312632; doi: https://doi.org/10.1101/2024.08.27.24312632

Inflammatory factors and risk of lung adenocarcinoma: a Mendelian randomization study mediated by blood metabolites

Ding Z, Chen J, Li B, Ji X.

Front Endocrinol (Lausanne). 2024 Aug 27;15:1446863. doi: 10.3389/fendo.2024.1446863.

Causal Effect of Tobacco Exposure on Acute Respiratory Distress Syndrome: A Mendelian Randomization Study

Yunfeng Wang, Zhihui Cheng, Dongwei Xu, Kan Shen, Jun Li, Shenghua Yan, Maofeng Zhou, Yingchao Qi, Hua Yu, Hui Ni, Lijun Liao, Yuling Li, Xingqi Deng

Researchsquare, 26 August 2024, doi: 10.21203/rs.3.rs-4806401/v1

Investigating the causal relationship between major depressive disorder and benign prostatic hyperplasia: a bidirectional Mendelian randomisation study

Zheng G, Xiao S, Cheng Y, Huang J, Luo C, Peng L, Zeng T.

Psychogeriatrics. 2024 Aug 26. doi: 10.1111/psyg.13180.

Associations Between Gut Microbiota and Alcohol Abuse: A Mendelian Randomisation and Bioinformatics Study

Wang X, Pan L, Gu J, Gu L, Lou M, Liu Y.

J Mol Neurosci. 2024 Aug 26;74(3):80. doi: 10.1007/s12031-024-02259-7.

Therapeutically targeting the classical complement pathway with antisense oligonucleotides in Alzheimer’s disease

Wang Y, Wu T, Gogineni A, Tsai M-C, Kielpinski L, Mahajan A, Pandey S, Schachner L, Tran JC, Wu C, Schauer S, Biever A, Boesen S, Li M, Munk A, Meilandt WJ, Elstrott J, Easton A, Gylling HM, Hanson JE.

bioRxiv 2024.08.23.609240; doi: https://doi.org/10.1101/2024.08.23.609240

Causal associations of obstructive sleep apnea with Chronic Respiratory Diseases: a Mendelian Randomization study

Hong PY, Liu D, Liu A, Su X, Zhang XB, Zeng YM.

BMC Pulm Med. 2024 Aug 26;24(1):409. doi: 10.1186/s12890-024-03228-x.

Primary immunodeficiency-related genes and varicella-zoster virus reactivation syndrome: a Mendelian randomization study

Wang H, Chen G, Gong Q, Wu J, Chen P.

Front Immunol. 2024 Aug 26;15:1403429. doi: 10.3389/fimmu.2024.1403429.

Elucidating the relationship between coffee consumption and obsessive-compulsive disorder: A Mendelian randomization study

Jiawei Wang, Minyan Feng, Zhiguo Li, Weifan Li

Researchsquare, 26 August 2024, doi: 10.21203/rs.3.rs-4724718/v1

A Two-Sample Mendelian Randomization Study of Neuroticism and Sleep Bruxism

Strausz T, Strausz S, Jones SE, Palotie T, Lobbezoo F, Ahlberg J, Ollila HM.

J Dent Res. 2024 Aug 26:220345241264749. doi: 10.1177/00220345241264749.

Metabolic factors are not the direct mediators of the association between type 2 diabetes and osteoporosis

Yang Q, Wang X, Liu Y, Liu J, Zhu D.

Front Endocrinol (Lausanne). 2024 Jul 25;15:1404747. doi: 10.3389/fendo.2024.1404747.

Causal associations of osteoporosis with stroke: a bidirectional Mendelian randomization study

Fan Z, Zhao J, Chen J, Hu W, Ma J, Ma X.

Osteoporos Int. 2024 Aug 24. doi: 10.1007/s00198-024-07235-w.

Causal relationships between gut microbiome and obstructive sleep apnea: a bi-directional Mendelian randomization

Liu L, He G, Yu R, Lin B, Lin L, Wei R, Zhu Z, Xu Y.

Front Microbiol. 2024 Aug 23;15:1410624. doi: 10.3389/fmicb.2024.1410624.

Causal association between blood leukocyte counts and vascular dementia: a two-sample bidirectional Mendelian randomization study

Liu S, Zhang C, Zhang Y, Wu Z, Wu P, Tian S, Zhang M, Lang L, Li L, Wang R, Liu H, Zhang J, Mao X, Li S.

Sci Rep. 2024 Aug 23;14(1):19582. doi: 10.1038/s41598-024-70446-y.

Relationship of Hypothyroidism with Alopecia Areata and Androgenetic Alopecia: Insights from a Two-Sample Mendelian Randomization Study

Zhang G, Huang X, Li H, Gong H, Zhou Y, Liu F.

Clin Cosmet Investig Dermatol. 2024 Aug 22;17:1865-1874. doi: 10.2147/CCID.S474168.

Causal relationship between genetically predicted antibody-Mediated Immune Responses and female infertility

Mo W, Zhang J, Peng X, Wang Y.

J Reprod Immunol. 2024 Aug 22;166:104319. doi: 10.1016/j.jri.2024.104319.

Association between gynecologic cancer and Alzheimer’s disease: a bidirectional mendelian randomization study

Cao D, Zhang S, Zhang Y, Shao M, Yang Q, Wang P.

BMC Cancer. 2024 Aug 21;24(1):1032. doi: 10.1186/s12885-024-12787-5.

Unique genetic and risk-factor profiles in clusters of major depressive disorder-related multimorbidity trajectories

Gezsi A, Van der Auwera S, Mäkinen H, Eszlari N, Hullam G, Nagy T, Bonk S, González-Colom R, Gonda X, Garvert L, Paajanen T, Gal Z, Kirchner K, Millinghoffer A, Schmidt CO, Bolgar B, Roca J, Cano I, Kuokkanen M, Antal P, Juhasz G.

Nat Commun. 2024 Aug 21;15(1):7190. doi: 10.1038/s41467-024-51467-7.

Deciphering the causal association and underlying transcriptional mechanisms between telomere length and abdominal aortic aneurysm

Zhang J, Xia X, He S.

Front Immunol. 2024 Aug 21;15:1438838. doi: 10.3389/fimmu.2024.1438838.

Causal Insights into Plasma Lipidome and Allergic Rhinitis: Implications from a Bidirectional Two-Sample Mendelian Randomization Analysis

Haoxiang Yang, Yaxin Luo, Qiang Liu

Researchsquare, 20 August 2024, doi: 10.21203/rs.3.rs-4617768/v1

Body Mass Index and Risk of Female Reproductive System Tumors Subtypes: A Meta-Analysis Using Mendelian Randomization

Jiang XY, Zheng L, Xiong M, Wang SL, Jin QQ, Yang YT, Fang YX, Hong L, Mei J, Zhou SG.

Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241277699. doi: 10.1177/15330338241277699.

Multiple sclerosis and abnormal spermatozoa: A bidirectional two-sample mendelian randomization study

Li B, Zhang L, Li Q, Zhang J, Wang W, Quan J.

PLoS One. 2024 Aug 20;19(8):e0308815. doi: 10.1371/journal.pone.0308815.

The Causal Effect of Intrapancreatic Fat Deposition on Acute and Chronic Pancreatitis: A Mendelian Randomization Study

Yamazaki H, Heni M, Wagner R, Fukuhara S, Grossman SR, Han S, Wu L, Streicher SA, Huang BZ.

Am J Gastroenterol. 2024 Dec 1;119(12):2540-2544. doi: 10.14309/ajg.0000000000003048.

Exploring the causal relationship between asthma in the metabolic syndrome: a Mendelian randomization study

Ru X, Huang L, Su Z, Ye C, Guo Y.

J Asthma. 2024 Aug 20:1-38. doi: 10.1080/02770903.2024.2394143.

Causal Effects of Smoking, Alcohol Consumption, and Coffee Intake on Hepatobiliary and Pancreatic Diseases: A Mendelian Randomization Study

Zhao B, Xue J, Zhang H.

Clin Res Hepatol Gastroenterol. 2024 Aug 19:102450. doi: 10.1016/j.clinre.2024.102450.

Physical activity, sedentary behavior, and risk of sepsis: a two-sample mendelian randomization study

Zhang Y, Rong Y, Mao J, Zhang J, Xiao W, Yang M.

Front Med (Lausanne). 2024 Aug 19;11:1436546. doi: 10.3389/fmed.2024.1436546.

Potential drug targets for osteoporosis identified: A Mendelian randomization study

Zhao G, Wang Q, Duan N, Zhang K, Li Z, Sun L, Lu Y.

Heliyon. 2024 Aug 19;10(16):e36566. doi: 10.1016/j.heliyon.2024.e36566.

Genetic Susceptibility of Thrombin Measurement Levels and the Risk of Colon Adenocarcinoma: A Mendelian Randomization Study

Liu Y, Zhou J.

Br J Hosp Med (Lond). 2024 Aug 30;85(8):1-13. doi: 10.12968/hmed.2024.0220.

The causal effect of gut microbiota on hepatic encephalopathy: a mendelian randomization analysis

Wu JL, Chen JW, Huang MS, Deng XY, Deng JJ, Lau TY, Cao SY, Ran HY, Jiang ZB, Luo JY.

BMC Med Genomics. 2024 Aug 19;17(1):216. doi: 10.1186/s12920-024-01939-y.

Genetics of transient amnesia highlights a vascular role in memory

Rivas MA, Daly MJ.

medRxiv 2024.08.18.24312185; doi: https://doi.org/10.1101/2024.08.18.24312185

Novel therapeutic targets for primary open-angle glaucoma identified through multicenter proteome-wide mendelian randomization

Yuan W, Li J, Gao S, Sun W, Zhao F.

Front Pharmacol. 2024 Aug 16;15:1428472. doi: 10.3389/fphar.2024.1428472.

Fibrosis to carcinogenesis: unveiling the causal dynamics between pulmonary fibrosis and lung cancer

Huang Y, Lin Z, Huang T, Zhou H.

Front Oncol. 2024 Aug 16;14:1452559. doi: 10.3389/fonc.2024.1452559.

Causal relationship between telomere length and osteonecrosis: Bidirectional two-sample Mendelian randomization analysis

Liu H, Yan W, Li J, Luo D, Yan D.

Medicine (Baltimore). 2024 Aug 16;103(33):e39324. doi: 10.1097/MD.0000000000039324.

No Evidence That Vitamin D Levels or Deficiency Are Associated with the Risk of Open-Angle Glaucoma in Individuals of European Ancestry: A Mendelian Randomisation Analysis

Kanso N, Hashimi M, Amin HA, Day AC, Drenos F.

Genes (Basel). 2024 Aug 16;15(8):1084. doi: 10.3390/genes15081084.

Lack of genetic association of non-melanoma skin cancer and pseudoexfoliative glaucoma

Beneke AA, Wiese JD, Root KT, Taneja K, Beal CJ.

Ophthalmic Genet. 2024 Aug 15:1-3. doi: 10.1080/13816810.2024.2390008

Intraocular pressure, primary open-angle glaucoma and the risk of retinal vein occlusion: A Mendelian randomization mediation analysis

Katsimpris A, Baumeister SE, Voulgari N, Hansjörg B, Kandarakis S, Nolde M.

Eye (Lond). 2024 Aug 15. doi: 10.1038/s41433-024-03303-x.

The causality between use of glucocorticoids and risk of pancreatitis: a Mendelian randomization study

Lin W, Zheng Q, Wang X, Lin X, Ni X, Pan J, Zippi M, Fiorino S, Hong W.

Front Immunol. 2024 Aug 15;15:1420840. doi: 10.3389/fimmu.2024.1420840.

Novel insights into causal effects of maternal nonalcoholic fatty liver disease on adverse pregnancy outcomes: evidence from Human Genetics and Mendelian Randomization Study

Luo Q, Liu G, Li Q, Lu J, Zheng W, Huang Y, Li C.

Eur J Clin Nutr. 2024 Dec;78(12):1041-1050. doi: 10.1038/s41430-024-01489-7.

Exploring the Germline Genetics of In Situ and Invasive Cutaneous Melanoma: A Genome-Wide Association Study Meta-Analysis

Ingold N, Seviiri M, Ong JS, Neale RE, Pandeya N, Whiteman DC, Olsen CM, Martin NG, Duffy DL, Khosrotehrani K, Hayward N, Montgomery GW, MacGregor S, Law MH.

JAMA Dermatol. 2024 Aug 14. doi: 10.1001/jamadermatol.2024.2601.

Abdominal multi-organ iron content and the risk of Parkinson's disease: a Mendelian randomization study

Yang M, Tang C, Peng F, Luo C, Chen G, Kong R, Peng P.

Front Aging Neurosci. 2024 Aug 14;16:1416014. doi: 10.3389/fnagi.2024.1416014.

Genetically Determined Circulating Saturated and Unsaturated Fatty Acids and the Occurrence and Exacerbation of Chronic Obstructive Pulmonary Disease-A Two-Sample Mendelian Randomization Study

Liu ZM, Chen YM, Chen CG, Wang C, Li MM, Guo YB.

Study. Nutrients. 2024 Aug 14;16(16):2691. doi: 10.3390/nu16162691.

Causal associations between fluid intake patterns and dermatitis risk: a Mendelian randomization study

Zeng R, Guo B, Liao W, Zhuan K, Chen H, Qin Z, Lin J, Gu T, Zhou Z.

Front Nutr. 2024 Aug 14;11:1416619. doi: 10.3389/fnut.2024.1416619.

Plasma Short-Chain Fatty Acids and Hypertensive Disorders of Pregnancy

Wang D, Wu L, Feng P, Sun Y, Wu D, Xu H, Peng H, Li H.