Julkaisulista

Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.

2024

Syyskuu

The potential causal relationship between BMI, T1D, urolithiasis, and hydronephrosis in European ancestry: A Mendelian randomization analysis

Han Y, Gao W, Wang B, Gao Z, Diao M, Zuo C, Zhang M, Diao Y, Wang C, Liu H, Gu Y.

Medicine (Baltimore). 2024 Sep 27;103(39):e39914. doi: 10.1097/MD.0000000000039914.

Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids

Lichtenstein L, Cheng CW, Bajarwan M, Evans EL, Gaunt HJ, Bartoli F, Chuntharpursat-Bon E, Patel S, Konstantinou C, Futers TS, Reay M, Parsonage G, Moore JB, Bertrand-Michel J, Sukumar P, Roberts LD, Beech DJ.

Sci Adv. 2024 Sep 27;10(39):eadq3075. doi: 10.1126/sciadv.adq3075.

Exploring and validating the necroptotic gene regulation and related lncRNA mechanisms in colon adenocarcinoma based on multi-dimensional data

Wang W, Liu Y, Wang Z, Tan X, Jian X, Zhang Z.

Sci Rep. 2024 Sep 27;14(1):22251. doi: 10.1038/s41598-024-73168-3.

Investigating causal links between gallstones, cholecystectomy, and 33 site-specific cancers: a Mendelian randomization post-meta-analysis study

Teng F, Tang Y, Lu Z, Chen K, Chen Z.

BMC Cancer. 2024 Sep 27;24(1):1192. doi: 10.1186/s12885-024-12906-2.

Association of air pollutants with psychiatric disorders: a two-sample Mendelian randomization

Ma YY, Li QY, Shi AY, Li JL, Wang YJ, Li X.

Ecotoxicol Environ Saf. 2024 Oct 15;285:117105. doi: 10.1016/j.ecoenv.2024.117105.

Polygenic scores for complex traits are associated with changes in concentration of circulating lipid species

Tabassum R, Mars N, Parolo PDB, Gerl MJ, Klose C; FinnGen; Pirinen M, Simons K, Widén E, Ripatti S.

PLoS Biol. 2024 Sep 26;22(9):e3002830. doi: 10.1371/journal.pbio.3002830.

Causal effect of thyroid cancer on secondary primary malignancies: findings from the UK Biobank and FinnGen cohorts

Wang Z, Rixiati Y, Jia C, Xu Y, Yin Z, Huang J, Dai J, Zhang Y.

Front Immunol. 2024 Sep 26;15:1434737. doi: 10.3389/fimmu.2024.1434737.

Investigating the uncertain causal link between gut microbiota and glaucoma: A genetic correlation and Mendelian randomisation study

Li J, Ma X, Zhuo K, He Y, Lin M, Wang W, Guo S, Tang C, Zhang X, Gao X.

Clin Exp Ophthalmol. 2024 Sep 26. doi: 10.1111/ceo.14440.

Effect of the gut microbiome and inflammation-related proteins on oral leukoplakia: a Mendelian randomization study and mediation analysis

Da J, Ren Y, Liu S, Wang N, Wang L, Fu Z, Liang Y, Pan Y, Li J, Chen J.

Front Oncol. 2024 Sep 25;14:1443123. doi: 10.3389/fonc.2024.1443123.

GNN4DM: a graph neural network-based method to identify overlapping functional disease modules

Gézsi A, Antal P.

Bioinformatics. 2024 Oct 1;40(10):btae573. doi: 10.1093/bioinformatics/btae573.

Exploring the Causal Association between Morning Diurnal Preference and Psychiatric Disorders: A Bidirectional Two-Sample Mendelian Randomization Analysis

Chen M, Tan DS, Wang X, Ye Z, Xie Z, Zhang D, Wu D, Zhao Y, Qu Y, Jiang Y.

Life (Basel). 2024 Sep 25;14(10):1225. doi: 10.3390/life14101225.

Assessing the causal association of sleep abnormalities with preeclampsia and eclampsia: a Mendelian randomization analysis

Li J, Kong Y, Shi G, Dong S, Wang X, Feng L, Guo Q, Lu C.

Hypertens Pregnancy. 2024 Dec;43(1):2405857. doi: 10.1080/10641955.2024.2405857.

Life-course obesity and heart failure: a two-sample Mendelian randomization study

Wang H, Min J, Zhong L, Zhang J, Ye L, Chen C.

Intern Emerg Med. 2024 Sep 24. doi: 10.1007/s11739-024-03772-8.

Genetic correlation between chronic sinusitis and autoimmune diseases

Wang E, Sun Y, Zhao H, Wang M, Cao Z.

Front Allergy. 2024 Sep 24;5:1387774. doi: 10.3389/falgy.2024.1387774.

Tea intake and non-alcoholic fatty liver disease risk: A two-sample Mendelian randomization study

Lu C, Ke L, Mentis AA, Zhang Q, Wang Z, Wang Z.

Metabol Open. 2024 Sep 24;24:100322. doi: 10.1016/j.metop.2024.100322.

Causal associations of air pollution with rheumatoid arthritis: A transethnic Mendelian randomization study

He A, Li H, Ouyang S, He J, Gong Z, Zhou Q, Wang S, Zhao X.

PLoS One. 2024 Sep 24;19(9):e0307514. doi: 10.1371/journal.pone.0307514.

Causal relationships between obesity-related anthropometric indicators and sepsis risk: a Mendelian-randomization study

Zhang C, Ren J, Xu X, Lei H, Deng G, Liu J, Gao X, Li J, Wang X, Wang G.

Front Nutr. 2024 Sep 23;11:1433754. doi: 10.3389/fnut.2024.1433754.

Bayesian-based analysis of the causality between 731 immune cells and erectile dysfunction: a two-sample, bidirectional, and multivariable Mendelian randomization study

Chen J, Liu Y, Zhan P, Gao T, Zuo J, Li X, Zhang F, Wang H, Fu S.

Sex Med. 2024 Sep 21;12(4):qfae062. doi: 10.1093/sexmed/qfae062.

Dissecting causal relationships between gut microbiome, immune cells, and brain injury: A Mendelian randomization study

Xian L, Xu X, Mai Y, Guo T, Chen Z, Deng X.

Medicine (Baltimore). 2024 Sep 20;103(38):e39740. doi: 10.1097/MD.0000000000039740.

The potential protective effect of 3-Hydroxybutyrate against aortic dissection: a mendelian randomization analysis

Qiu S, Liu Z, Wang CT, Sun XD, Liu ZQ, Liu W.

Nutr Metab (Lond). 2024 Sep 20;21(1):75. doi: 10.1186/s12986-024-00853-5.

Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders

Tesfaye M, Jaholkowski P, Shadrin AA, van der Meer D, Hindley GFL, Holen B, Parker N, Parekh P, Birkenæs V, Rahman Z, Bahrami S, Kutrolli G, Frei O, Djurovic S, Dale AM, Smeland OB, O'Connell KS, Andreassen OA.

Psychiatry Clin Neurosci. 2024 Dec;78(12):783-791. doi: 10.1111/pcn.13742.

Genetic susceptibility to acute viral bronchiolitis

Pasanen A, Karjalainen MK, Korppi M, Hallman M, Rämet M; Research Project FinnGen.

J Infect Dis. 2024 Sep 20:jiae467. doi: 10.1093/infdis/jiae467.

Sedentary and 21 gastrointestinal disorders: A Mendelian randomization study

Lin Y, He J, Ding Z.

Medicine (Baltimore). 2024 Sep 20;103(38):e39813. doi: 10.1097/MD.0000000000039813.

Unveiling genetic links between gut microbiota and asthma: a Mendelian randomization

Zheng X, Chen M, Zhuang Y, Zhao L, Qian Y, Shi C.

Front Microbiol. 2024 Sep 20;15:1448629. doi: 10.3389/fmicb.2024.1448629.

Bidirectional Mendelian randomization explores the causal relationship between dietary habits and rheumatoid arthritis

Xu W, Ouyang M, Peng D, Jiang Z.

Medicine (Baltimore). 2024 Sep 20;103(38):e39779. doi: 10.1097/MD.0000000000039779.

Polymyalgia rheumatica and giant cell arteritis: A bidirectional Mendelian randomization study

Teng L, Li L, Cui D, An R, Jin J.

Medicine (Baltimore). 2024 Sep 20;103(38):e39723. doi: 10.1097/MD.0000000000039723.

Causal effects of post-traumatic stress disorder on autoimmune thyroid disease: insights from mendelian randomization

Chen Z, Yu Y, Yao J, Guo Z, Cui Y, Li F, Li C.

Front Psychiatry. 2024 Sep 20;15:1417302. doi: 10.3389/fpsyt.2024.1417302.

Unraveling the causative connection between urticaria, inflammatory cytokines, and mental disorders: Perspectives from genetic evidence

Liu Z, Wang Y, Wang S, Wu J, Jia C, Tan X, Liu X, Huang X, Zhang L.

Skin Res Technol. 2024 Sep;30(9):e13906. doi: 10.1111/srt.13906.

Associations between human blood metabolome and vascular dementia

Jia Y, Guo D, Liu Y, Sun L, Chang X, He Y, Shi M, Chen GC, Zhang Y, Hui L, Zhu Z.

Prog Neuropsychopharmacol Biol Psychiatry. 2024 Sep 19;136:111150. doi: 10.1016/j.pnpbp.2024.111150.

Genetically predicted frailty index and risk of chronic kidney disease

Chen HJ, Qiu J, Guo Y, Chen F.

Sci Rep. 2024 Sep 19;14(1):21862. doi: 10.1038/s41598-024-71881-7.

Causal Relationship Between Mood Swing and Gynecological Disorders: A Mendelian Randomization Study

Bian J, Li H, Shang Y, Zhang F, Tang L.

Int J Womens Health. 2024 Sep 19;16:1541-1549. doi: 10.2147/IJWH.S468624.

No genetic causal relationship between acne and prostate cancer through Mendelian randomization combined with meta-analysis

He M, Wang X, Wang D, Wang Y, Qi J, Jia J, Zhang M, Meng Q, Yan B, Guo H, Qu C.

Front Oncol. 2024 Sep 19;14:1460467. doi: 10.3389/fonc.2024.1460467.

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study

Friligkou E, Løkhammer S, Cabrera-Mendoza B, Shen J, He J, Deiana G, Zanoaga MD, Asgel Z, Pilcher A, Di Lascio L, Makharashvili A, Koller D, Tylee DS, Pathak GA, Polimanti R.

Nat Genet. 2024 Oct;56(10):2036-2045. doi: 10.1038/s41588-024-01908-2.

Investigating the causal link between gut microbiota and dry age-related macular degeneration: a bidirectional Mendelian randomization study

Huang HY, Wang J, Qin B, Tan Y.

Int J Ophthalmol. 2024 Sep 18;17(9):1723-1730. doi: 10.18240/ijo.2024.09.21.

Improving on polygenic scores across complex traits using select and shrink with summary statistics (S4) and LDpred2

Tyrer JP, Peng PC, DeVries AA, Gayther SA, Jones MR, Pharoah PD.

BMC Genomics. 2024 Sep 18;25(1):878. doi: 10.1186/s12864-024-10706-3.

Integrative multi-omics summary-based mendelian randomization identifies key oxidative stress-related genes as therapeutic targets for atrial fibrillation and flutter

Chen S, Sun J, Wen W, Chen Z, Yu Z.

Front Genet. 2024 Sep 18;15:1447872. doi: 10.3389/fgene.2024.1447872.

Allium Vegetables Intake and Digestive System Cancer Risk: A Study Based on Mendelian Randomization, Network Pharmacology and Molecular Docking

Li S, Lou J, Mulatihan Y, Xiong Y, Li Y, Xu Q.

medRxiv 2024.09.18.24313801; doi: https://doi.org/10.1101/2024.09.18.24313801

Causal Relationships of Circulating Inflammatory Proteins and Portal Vein Thrombosis: A Mendelian Randomization Study

Zhang B, Yao Z, Li P, Niu G, Yan Z, She K, Cheng G, Yang M.

Semin Thromb Hemost. 2024 Sep 18. doi: 10.1055/s-0044-1790259.

Landscape of stroke comorbidities: A disease-wide association study

Zheng M, Lavie CJ.

Prog Cardiovasc Dis. 2024 Sep-Oct;86:96-99. doi: 10.1016/j.pcad.2024.09.005.

Genetic Distinctions Between Reticular Pseudodrusen and Drusen: Insights from a Genome-Wide Association Study

Schwartz R, Warwick AN, Khawaja AP, Luben R, Khalid H, Phatak S, Jhingan M, de Vente C, Valmaggia P, Liakopoulos S, Olvera-Barrios A, Sánchez CI, Egan C, Bonelli R, Tufail A.

medRxiv 2024.09.18.24313862; doi: https://doi.org/10.1101/2024.09.18.24313862

A Two-step Bayesian Mendelian Randomization Study on Cholecystitis and Dermatitis

Zhao C, Cen C, Zhang R, He W, Jiao Y, Chen Z, Wu Z, Luan T.

medRxiv 2024.09.17.24313850; doi: https://doi.org/10.1101/2024.09.17.24313850

Causal effects of gut microbiota, metabolites, immune cells, liposomes, and inflammatory proteins on anorexia nervosa: A mediation joint multi-omics Mendelian randomization analysis

Li Z, Bi T.

J Affect Disord. 2024 Sep 17;368:343-358. doi: 10.1016/j.jad.2024.09.115.

Variant scoring performance across selection regimes depends on variant-to-gene and gene-to-disease components

Finucane HK, Parsa S, Guez J, Kanai M, Satterstrom FK, Nkambule LL, Daly MJ, Seed C, Karczewski KJ.

bioRxiv 2024.09.17.613327; doi: https://doi.org/10.1101/2024.09.17.613327

Association of Obstructive Sleep Apnea on Heart Failure and Its Risk Factors: A Two-Step Mendelian Randomization Study

Liu J, Chen Z, Cai D.