Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.
2024

Huhtikuu

Causal effects of neuroticism on postpartum depression: a bidirectional mendelian randomization study
Hu Q, Chen J, Ma J, Li Y, Xu Y, Yue C, Cong E.
Arch Womens Ment Health. 2024 Apr 18. doi: 10.1007/s00737-024-01466-w.
Reverse causation between multiple sclerosis and psoriasis: a genetic correlation and Mendelian randomization study
Zhou H, Qi Y, Xu Y, Qi X, Qi H.
Sci Rep. 2024 Apr 17;14(1):8845. doi: 10.1038/s41598-024-58182-9.
Osteoarthritis and hypertension: observational and Mendelian randomization analyses
Yang ZJ, Liu Y, Liu YL, Qi B, Yuan X, Shi WX, Miao L.
Arthritis Res Ther. 2024 Apr 17;26(1):88. doi: 10.1186/s13075-024-03321-w.
Refining the impact of genetic evidence on clinical success
Minikel EV, Painter JL, Dong CC, Nelson MR.
Nature. 2024 May;629(8012):624-629. doi: 10.1038/s41586-024-07316-0.
Multiple reports on the causal relationship between various chronic pain and gut microbiota: a two-sample Mendelian randomization study
Cai Y, Wen S, Hu J, Wang Z, Huang G, Zeng Q, Zou J.
Front Neurosci. 2024 Apr 17;18:1369996. doi: 10.3389/fnins.2024.1369996.
Effects of saturated and monounsaturated fatty acids on cognitive impairment: evidence from Mendelian randomization study
Zeng Y, Cao S, Tang J, Lin G.
Eur J Clin Nutr. 2024 Jul;78(7):585-590. doi: 10.1038/s41430-024-01437-5.
Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencing
Liu X, Koyama S, Tomizuka K, Takata S, Ishikawa Y, Ito S, Kosugi S, Suzuki K, Hikino K, Koido M, Koike Y, Horikoshi M, Gakuhari T, Ikegawa S, Matsuda K, Momozawa Y, Ito K, Kamatani Y, Terao C.
Sci Adv. 2024 Apr 19;10(16):eadi8419. doi: 10.1126/sciadv.adi8419.
Critically-ill COVID-19 susceptibility gene CCR3 shows natural selection in sub-Saharan Africans
Sun Z, Pan L, Tian A, Chen P.
Infect Genet Evol. 2024 Apr 16;121:105594. doi: 10.1016/j.meegid.2024.105594.
Genetically predicted biomarkers of iron homeostasis and risk of non-ischemic cardiomyopathy: A mendelian randomization study
Huang H, Wang X, Yu Y, Cheng S, Long T, Niu H, Hua W.
Nutr Metab Cardiovasc Dis. 2024 Apr 16:S0939-4753(24)00156-X. doi: 10.1016/j.numecd.2024.04.006.
Causal relationship between circulating cytokines and follicular lymphoma: a two-sample Mendelian randomization study
Sun C, Liu C, Liu X, Wu Z, Luo J, Liu R, Wang Y, Lu M, Wang Q, Guo M, Tang Y, Li X, Zheng J.
Am J Cancer Res. 2024 Apr 15;14(4):1577-1593. doi: 10.62347/JCKD6973.
Protective effect of higher free thyroxine levels within the reference range on biliary tract cancer risk: a multivariable mendelian randomization and mediation analysis
Chen Y, Dong H, Qu B, Ma X, Lu L.
Front Endocrinol (Lausanne). 2024 Apr 15;15:1379607. doi: 10.3389/fendo.2024.1379607.
Body mass index and meniscal tears: Evidence from meta-analysis of observational studies and Mendelian randomization
Lee JH, Oh S, Kim K, Lee D, Son E, Kim TW, Goh TS, Cho NR, Kim YH.
Obes Rev. 2024 Apr 14:e13749. doi: 10.1111/obr.13749.
Kidney Function and Cardiovascular Disease: Evidence from Observational Studies and Mendelian Randomization Analyses
Yang W, Wu X, Zhao M, Hu J, Lin C, Mei Z, Chen J, Zhou XJ, Nie S, Nie J, Gao X, Zheng Y, Sun Z.
Phenomics. 2024 Apr 13;4(3):250-253. doi: 10.1007/s43657-023-00145-7.
Causal influence of celiac disease on the risk of sarcoidosis: A Mendelian randomization study
Zhou Z, Chen Y, Wang L.
Medicine (Baltimore). 2024 Apr 12;103(15):e37736. doi: 10.1097/MD.0000000000037736.
Genetic insights into gut microbiota and risk of prostatitis: a Mendelian randomization study
Qin P, He Y, Shao H, Jiang D.
Front Microbiol. 2024 Apr 12;15:1389715. doi: 10.3389/fmicb.2024.1389715.
Genetically predicted dietary macronutrient intakes and atrial fibrillation risk: a Mendelian randomization study
Zhang Z, Zhang J, Jiao H, Tian W, Zhai X.
Eur J Med Res. 2024 Apr 12;29(1):227. doi: 10.1186/s40001-024-01781-z.
The genetic association between hyperthyroidism and heart failure: a Mendelian randomization study
Liu J, Wu G, Li S, Cheng L, Ye X.
Front Endocrinol (Lausanne). 2024 Apr 12;15:1344282. doi: 10.3389/fendo.2024.1344282.
Exploring the Associations of Inflammatory and Oxidative Stress Biomarkers with Pancreatic Diseases: An Observational and Mendelian Randomisation Study
Vilà-Quintana L, Fort E, Pardo L, Albiol-Quer MT, Ortiz MR, Capdevila M, Feliu A, Bahí A, Llirós M, Aguilar E, García-Velasco A, Ginestà MM, Laquente B, Pozas D, Lluansí A, Pimenoff VN, Moreno V, Garcia-Gil LJ, Duell EJ, Carreras-Torres R, Aldeguer X.
J Clin Med. 2024 Apr 12;13(8):2247. doi: 10.3390/jcm13082247.
Human Genetics and Genomics for Drug Target Identification and Prioritization: Open Targets' Perspective
McDonagh EM, Trynka G, McCarthy M, Holzinger ER, Khader S, Nakic N, Hu X, Cornu H, Dunham I, Hulcoop D.
Annu Rev Biomed Data Sci. 2024 Apr 12. doi: 10.1146/annurev-biodatasci-102523-103838.
Association of genetically predicted 486 blood metabolites on the risk of Alzheimer's disease: a Mendelian randomization study
Yang Q, Han X, Ye M, Jiang T, Wang B, Zhang Z, Li F.
Front Aging Neurosci. 2024 Apr 12;16:1372605. doi: 10.3389/fnagi.2024.1372605.
Lifestyle factors, glycemic traits, and lipoprotein traits and risk of liver cancer: a Mendelian randomization analysis
Zhang H, Liu J.
Sci Rep. 2024 Apr 12;14(1):8502. doi: 10.1038/s41598-024-59211-3.
Genetic susceptibility of urolithiasis: comprehensive results from genome-wide analysis
Lin L, Ma Y, Li Z, Liu L, Hu Q, Zhou L.
World J Urol. 2024 Apr 12;42(1):230. doi: 10.1007/s00345-024-04937-y.
Inflammatory cytokine profiles in erectile dysfunction: a bidirectional Mendelian randomization
Liu D, Qin Z, Yi B, Xie H, Liang Y, Zhu L, Yang K, Zhang H.
Front Immunol. 2024 Apr 12;15:1342658. doi: 10.3389/fimmu.2024.1342658.
Type 1 diabetes mellitus and non-alcoholic fatty liver disease: a two-sample Mendelian randomization study
Tuo L, Yan LT, Liu Y, Yang XX.
Front Endocrinol (Lausanne). 2024 Apr 12;15:1315046. doi: 10.3389/fendo.2024.1315046.
Evaluation of bi-directional causal association between periodontitis and benign prostatic hyperplasia: epidemiological studies and two-sample mendelian randomization analysis
Wei H, Tian G, Xu S, Du Y, Li M, Wang Y, Deng J, Quan C.
Front Genet. 2024 Apr 10;15:1326434. doi: 10.3389/fgene.2024.1326434.
Genetically identification of endometriosis and cancers risk in women through a two-sample Mendelian randomization study
Zhang L, Yan H.
Sci Rep. 2024 Apr 10;14(1):8382. doi: 10.1038/s41598-024-58950-7.
Matrix metalloproteinase and aortic aneurysm: a two-sample Mendelian randomization study
Qin T, Zhong J, Li P, Liang J, Li M, Zhang G.
Ann Vasc Surg. 2024 Apr 10:S0890-5096(24)00177-8. doi: 10.1016/j.avsg.2024.02.011.
Mendelian randomization analysis identifies druggable genes and drugs repurposing for chronic obstructive pulmonary disease
Wang Z, Li S, Cai G, Gao Y, Yang H, Li Y, Liang J, Zhang S, Hu J, Zheng J.
Front Cell Infect Microbiol. 2024 Apr 10;14:1386506. doi: 10.3389/fcimb.2024.1386506.
Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles
Sakaue S, Weinand K, Isaac S, Dey KK, Jagadeesh K, Kanai M, Watts GFM, Zhu Z; Accelerating Medicines Partnership® RA/SLE Program and Network; Brenner MB, McDavid A, Donlin LT, Wei K, Price AL, Raychaudhuri S.
Nat Genet. 2024 Apr;56(4):615-626. doi: 10.1038/s41588-024-01682-1.
Causal relationship between the immune cells and ankylosing spondylitis: univariable, bidirectional, and multivariable Mendelian randomization
Qin C, Yu Q, Deng Z, Zhang Y, Chen M, Wang X, Hu T, Lei B, Yan Z, Cheng S.
Front Immunol. 2024 Apr 9;15:1345416. doi: 10.3389/fimmu.2024.1345416.
Interaction of immune cells with renal cancer development: Mendelian randomization (MR) study
Lu Z, Yin Y, Rao T, Xu X, Zhao K, Liu Z, Qin C, Tang M.
BMC Cancer. 2024 Apr 9;24(1):439. doi: 10.1186/s12885-024-12196-8.
Risk relationship between inflammatory bowel disease and urolithiasis: A two-sample Mendelian randomization study
Fu W, Zhu B, Chen J, Jin X.
PLoS One. 2024 Apr 9;19(4):e0301545. doi: 10.1371/journal.pone.0301545.
Differential Causal Effects of Type 1 and Type 2 Diabetes on Osteomyelitis Risk: Insights from Mendelian Randomization Analysis
Li Y, Zhou C, Yang L, Tan L.
medRxiv 2024.04.08.24305482; doi: https://doi.org/10.1101/2024.04.08.24305482
Exploring the immunological landscape of osteomyelitis through mendelian randomization analysis
Long K, Gong A, Yu D, Dong S, Ying Z, Zhang L.
Front Genet. 2024 Apr 8;15:1362432. doi: 10.3389/fgene.2024.1362432.
Associations between ticagrelor use and the risk of infections: A Mendelian randomization study
Xia M, Wu Q, Wang Y, Peng Y, Qian C.
J Infect Dis. 2024 Apr 8:jiae177. doi: 10.1093/infdis/jiae177.
Genetic causal relationship between immune diseases and migraine: a Mendelian randomization study
Li G, Duan S; International Headache Genetics Consortium (IHGC); Zheng T, Zhu T, Qu B, Liu L, Liu Z.
Front Immunol. 2024 Apr 8;15:1376698. doi: 10.3389/fimmu.2024.1376698.
Interplay Between Plasma Glycine and Branched-Chain Amino Acids Contributes to the Development of Hypertension and Coronary Heart Disease
Dziedzic M, Józefczuk E, Guzik TJ, Siedlinski M.
Hypertension. 2024 Apr 8. doi: 10.1161/HYPERTENSIONAHA.123.22649.
Identification of potential therapeutic targets for breast cancer using Mendelian randomization analysis and drug target prediction
Huang Z, Zheng H, Wang H, Ning H, Che A, Cai C.
Environ Toxicol. 2024 Apr 6. doi: 10.1002/tox.24249.
Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis
Chen J, Ruan X, Fu T, Lu S, Gill D, He Z, Burgess S, Giovannucci EL, Larsson SC, Deng M, Yuan S, Li X.
EBioMedicine. 2024 Apr 6;103:105110. doi: 10.1016/j.ebiom.2024.105110.
Assessing the causal link between liver function and acute pancreatitis: A Mendelian randomisation study
Zhang C, Lin F, Guo DF, Wang QL, Xiao DX, Lin JY, Chen S.
PLoS One. 2024 Apr 5;19(4):e0300890. doi: 10.1371/journal.pone.0300890.
Love-hate relationship between hepatitis B virus and type 2 diabetes: a Mendelian randomization study
Yu Y, Tong K, Hu G, Yang X, Wu J, Bai S, Yu R.
Front Microbiol. 2024 Apr 5;15:1378311. doi: 10.3389/fmicb.2024.1378311.
Investigating genetic links between blood metabolites and preeclampsia
Lin Q, Li S, Wang H, Zhou W.
BMC Womens Health. 2024 Apr 5;24(1):223. doi: 10.1186/s12905-024-03000-7.
Causal associations of particulate matter 2.5 and cardiovascular disease: A two-sample mendelian randomization study
Cao Y, Feng Y, Xia N, Zhang J.
PLoS One. 2024 Apr 5;19(4):e0301823. doi: 10.1371/journal.pone.0301823.
Causality between cathepsins and idiopathic pulmonary fibrosis: a Mendelian randomization study
Zhuen Zhong, Ruochen Xu, Changhao Xu, Yanlin Zhu, Qian Xu, Yan Hua
Researchsquare, 05 April 2024, doi: 10.21203/rs.3.rs-4190026/v1
Evaluation of the genetic architecture of human blood metabolites on sudden cardiac arrest: A Mendelian randomization analysis
Xisha Tang, Hui Jia Zhuang, Hai Yu
Researchsquare, 05 April 2024, doi: 10.21203/rs.3.rs-4011125/v1
Serum albumin and cardiovascular disease: a Mendelian randomization study
Huang T, An Z, Huang Z, Gao W, Hao B, Xu J.
BMC Cardiovasc Disord. 2024 Apr 5;24(1):196. doi: 10.1186/s12872-024-03873-4.
No genetic causality between obesity and benign paroxysmal vertigo: A two-sample Mendelian randomization study
Guo Z, Huang B, Gan L, Liang S, Liu Y.
Open Med (Wars). 2024 Apr 5;19(1):20240940. doi: 10.1515/med-2024-0940.
Causal effect of gut microbiota on the risk of prostatitis: a two-sample Mendelian randomization study
Liu D, Mei Y, Ji N, Zhang B, Feng X.
Int Urol Nephrol. 2024 Apr 4. doi: 10.1007/s11255-024-04020-w.
Systematic proteome-wide Mendelian randomization using the human plasma proteome to identify therapeutic targets for lung adenocarcinoma
Zhang L, Xiong Y, Zhang J, Feng Y, Xu A.
J Transl Med. 2024 Apr 4;22(1):330. doi: 10.1186/s12967-024-04919-z.
Identification of prospective aging drug targets via Mendelian randomization analysis
Mao R, Li J, Xiao W.
Aging Cell. 2024 Apr 4:e14171. doi: 10.1111/acel.14171.