Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.
2020

Huhtikuu

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers
Mars N, Koskela JT, Ripatti P, Kiiskinen TTJ, Havulinna AS, Lindbohm JV, Ahola-Olli A, Kurki M, Karjalainen J, Palta P; FinnGen, Neale BM, Daly M, Salomaa V, Palotie A, Widén E, Ripatti S.
Nat Med. 2020 Apr;26(4):549-557. doi: 10.1038/s41591-020-0800-0.

Maaliskuu

Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan
Sakaue S, Kanai M, Karjalainen J, Akiyama M, Kurki M, Matoba N, Takahashi A, Hirata M, Kubo M, Matsuda K, Murakami Y; FinnGen, Daly MJ, Kamatani Y, Okada Y.
Nat Med. 2020 Apr;26(4):542-548. doi: 10.1038/s41591-020-0785-8.
Polygenic Hyperlipidemias and Coronary Artery Disease Risk
Ripatti P, Rämö JT, Mars NJ, Fu Y, Lin J, Söderlund S, Benner C, Surakka I, Kiiskinen T, Havulinna AS, Palta P, Freimer NB, Widén E, Salomaa V, Tukiainen T, Pirinen M, Palotie A, Taskinen MR, Ripatti S; FinnGen†.
Circ Genom Precis Med. 2020 Apr;13(2):e002725. doi: 10.1161/CIRCGEN.119.002725.

Tammikuu

Genomic prediction of alcohol-related morbidity and mortality
Kiiskinen T, Mars NJ, Palviainen T, Koskela J, Rämö JT, Ripatti P, Ruotsalainen S; FinnGen, GSCAN Consortium, Palotie A, Madden PAF, Rose RJ, Kaprio J, Salomaa V, Mäkelä P, Havulinna AS, Ripatti S.
Transl Psychiatry. 2020 Jan 21;10(1):23. doi: 10.1038/s41398-019-0676-2.
2019

Lokakuu

Phenome-wide association study of TTR and RBP4 genes in 361,194 individuals reveals novel insights in the genetics of hereditary and wildtype transthyretin amyloidoses
De Lillo A, De Angelis F, Di Girolamo M, Luigetti M, Frusconi S, Manfellotto D, Fuciarelli M, Polimanti R.
Hum Genet. 2019 Dec;138(11-12):1331-1340. doi: 10.1007/s00439-019-02078-6.
CCR5-del32 is not deleterious in the homozygous state in humans
Gudbjartsson D, Sulem P, Stefansson K, Mars N, Karjalainen J, Ripatti S, Palotie A, Daly M.
bioRxiv 788117; doi: https://doi.org/10.1101/788117.

Syyskuu

Genetic architecture of human plasma lipidome and its link to cardiovascular disease
Tabassum R, Rämö JT, Ripatti P, Koskela JT, Kurki M, Karjalainen J, Palta P, Hassan S, Nunez-Fontarnau J, Kiiskinen TTJ, Söderlund S, Matikainen N, Gerl MJ, Surma MA, Klose C, Stitziel NO, Laivuori H, Havulinna AS, Service SK, Salomaa V, Pirinen M; FinnGen Project, Jauhiainen M, Daly MJ, Freimer NB, Palotie A, Taskinen MR, Simons K, Ripatti S.
Nat Commun. 2019 Sep 24;10(1):4329. doi: 10.1038/s41467-019-11954-8.

Heinäkuu

Exome sequencing of Finnish isolates enhances rare-variant association power
Locke AE, Steinberg KM, Chiang CWK, Service SK, Havulinna AS, Stell L, Pirinen M, Abel HJ, Chiang CC, Fulton RS, Jackson AU, Kang CJ, Kanchi KL, Koboldt DC, Larson DE, Nelson J, Nicholas TJ, Pietilä A, Ramensky V, Ray D, Scott LJ, Stringham HM, Vangipurapu J, Welch R, Yajnik P, Yin X, Eriksson JG, Ala-Korpela M, Järvelin MR, Männikkö M, Laivuori H; FinnGen Project, Dutcher SK, Stitziel NO, Wilson RK, Hall IM, Sabatti C, Palotie A, Salomaa V, Laakso M, Ripatti S, Boehnke M, Freimer NB.
Nature. 2019 Aug;572(7769):323-328. doi: 10.1038/s41586-019-1457-z.

Toukokuu

The validity of heart failure diagnoses in the Finnish Hospital Discharge Register
Vuori MA, Laukkanen JA, Pietilä A, Havulinna AS, Kähönen M, Salomaa V, Niiranen TJ; FinnGen investigators.
Scand J Public Health. 2020 Feb;48(1):20-28. doi: 10.1177/1403494819847051.