På den här sidan listar vi alla vetenskapliga publikationer som har använt data från FinnGen-studien.

2023

November

Genetically Proxied Therapeutic Effect of Metformin Use, Blood Pressure, and Hypertension's Risk: a Drug Target-Based Mendelian Randomization Study
Jiang J, Hu D, Zhang Q, Lin Z; μ-Biomedical Data Investigation Group (Mu-BioDig).
J Cardiovasc Transl Res. 2023 Nov 27. doi: 10.1007/s12265-023-10460-z.
Body composition and risk of gestational diabetes mellitus: A univariable and multivariable Mendelian randomization study
Gao Y, Zhou M, Xu X, Ma JY, Qin MF
J Diabetes Investig. 2023 Nov 27. doi: 10.1111/jdi.14115
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
Mälarstig A, Grassmann F, Dahl L, Dimitriou M, McLeod D, Gabrielson M, Smith-Byrne K, Thomas CE, Huang TH, Forsberg SKG, Eriksson P, Ulfstedt M, Johansson M, Sokolov AV, Schiöth HB, Hall P, Schwenk JM, Czene K, Hedman ÅK.
Nat Commun. 2023 Nov 24;14(1):7680. doi: 10.1038/s41467-023-43485-8.
Effect of Glucosamine on Intraocular Pressure and Risk of Developing Glaucoma
Lehrer S, Morello T, Karrasch C, Rheinstein PH, Danias J.
J Glaucoma. 2023 Nov 24. doi: 10.1097/IJG.0000000000002340.
Causal link between gut microbiota and four types of pancreatitis: a genetic association and bidirectional Mendelian randomization study
Wang K, Qin X, Ran T, Pan Y, Hong Y, Wang J, Zhang X, Shen X, Liu C, Lu X, Chen Y, Bai Y, Zhang Y, Zhou C, Zou D
Front Microbiol. 2023 Nov 23;14:1290202. doi: 10.3389/fmicb.2023.1290202
Causal relationship between gut microbiota and immune thrombocytopenia: a Mendelian randomization study of two samples
Guo D, Chen Q, Wang G, Li C; FinnGen consortium
Front Microbiol. 2023 Nov 23;14:1190866. doi: 10.3389/fmicb.2023.1190866
Genetically predicted causal associations between periodontitis and psychiatric disorders
Tong S, Lyu Y, Huang W, Zeng R, Jiang R, Lian Q, Leung FW, Sha W, Chen H
BMJ Ment Health. 2023 Nov 22;26(1):e300864. doi: 10.1136/bmjment-2023-300864
New insight into the causal relationship between Graves' disease liability and drug eruption: a Mendelian randomization study.
Wu D, Liu B, Xian W, Yang Y, Li J, Hong S, Li Y, Xiao H
Front Immunol. 2023 Nov 21;14:1267814. doi: 10.3389/fimmu.2023.1267814
Gut microbiota and risk of polycystic ovary syndrome: Insights from Mendelian randomization
Li JW, Chen YZ, Zhang Y, Zeng LH, Li KW, Xie BZ, Luo SP, Gao J
Heliyon. 2023 Nov 21;9(12):e22155. doi: 10.1016/j.heliyon.2023.e22155
Narcolepsy and psychiatric disorders: A bidirectional Mendelian randomization study
Li B, Gao Z, He Y, Tian Y, Shen Y, Yu G, Geng X, Kou C
J Psychiatr Res. 2023 Nov 21;169:42-48. doi: 10.1016/j.jpsychires.2023.11.034
Can periodontitis lead to adverse pregnancy outcomes: A Mendelian Randomization study
Tianxing Yan, Yiping Wei, Wenjie Hu
Researchsquare, 21 November 2023, doi:10.21203/rs.3.rs-3628808/v1
Causal association of calcific aortic valve stenosis and atrial fibrillation: a Mendelian randomization study
Chai C, Li S, Chen L, Song X
Sci Rep. 2023 Nov 20;13(1):20284. doi: 10.1038/s41598-023-47770-w
The causal relationship between physical activity, sedentary time and idiopathic pulmonary fibrosis risk: a Mendelian randomization study
Lei W, Yang M, Yuan Z, Feng R, Kuang X, Liu Z, Deng Z, Hu X, Tai W
Respir Res. 2023 Nov 20;24(1):291. doi: 10.1186/s12931-023-02610-3
The causal role of immune cells in rheumatoid arthritis: a Mendelian randomization study
wei yang, Zhenhua Li, Xiuzhen Han, Miao Cui, Mingze Han, Jianan Yu, Yi Qu, Haorui Shi
Researchsquare, 20 November 2023, doi:10.21203/rs.3.rs-3610819/v1
Genetics of sleep medication purchases suggests causality from sleep problems to psychiatric traits
Broberg M, Helaakoski V, Kiiskinen T, Paunio T, Jones SE, Mars N, Lane JM; FinnGen; Saxena R, Ollila HM
Sleep. 2023 Nov 20:zsad279. doi: 10.1093/sleep/zsad279
Roles of human gut microbiota in liver cirrhosis risk: a two-sample mendelian randomization study
Li O, Xu H, Kim D, Yang F, Bao Z
J Nutr. 2023 Nov 18:S0022-3166(23)72727-2. doi: 10.1016/j.tjnut.2023.11.011
Integrative genome-wide analyses identify novel loci associated with kidney stones and provide insights into its genetic architecture
Hao X, Shao Z, Zhang N, Jiang M, Cao X, Li S, Guan Y, Wang C
Nat Commun. 2023 Nov 18;14(1):7498. doi: 10.1038/s41467-023-43400-1
Gastroesophageal Reflux Disease and Rhinosinusitis: A Bidirectional Mendelian Randomization Study
Chen TY, Lv MH, Lai RJ, Hu YQ, Ye ZK, Lv QL, Chen BY, Wu JT, Hong H, Li S
Int Arch Allergy Immunol. 2023 Nov 17:1-8. doi: 10.1159/000534676
Intervertebral Disk Degeneration and Bone Mineral Density: A Bidirectional Mendelian Randomization Study
Zhao J, Wang J, Xu H, Hu W, Shi F, Fan Z, Zhou C, Mu H
Calcif Tissue Int. 2023 Nov 17. doi: 10.1007/s00223-023-01165-1
Causal Effect of Relative Carbohydrate Intake on Hypertension through Psychological Well-Being and Adiposity: A Mendelian Randomization Study
Ye C, Kong L, Wang Y, Dou C, Xu M, Zheng J, Zheng R, Xu Y, Li M, Zhao Z, Lu J, Chen Y, Wang W, Bi Y, Wang T, Ning G
Nutrients. 2023 Nov 17;15(22):4817. doi: 10.3390/nu15224817
Exploring the causal relationship between inflammatory cytokines and inflammatory arthritis: A Mendelian randomization study
Pan S, Wu S, Wei Y, Liu J, Zhou C, Chen T, Zhu J, Tan W, Huang C, Feng S, Zhang B, Wei W, Zhan X, Liu C
Cytokine. 2023 Nov 16;173:156446. doi: 10.1016/j.cyto.2023.156446.
The role of NSAID in mediating the effect of genetically predicted major depressive disorder on osteomyelitis: A Mendelian randomization study
Chen B, Pu B, Li S, Gong Y, Dong H
J Affect Disord. 2023 Nov 15;341:62-66. doi: 10.1016/j.jad.2023.08.121
Assessing the journey of calcium supplementation: A mendelian randomization study on the causal link between calcium levels and sleep disorders
Ma L, Huo Y, Peng T, Liu Z, Ye J, Chen L, Wu D, Du W, Chen J.
Clin Nutr ESPEN. 2024 Feb;59:1-8. doi: 10.1016/j.clnesp.2023.10.039.
Predicting the causal relationship between polyunsaturated fatty acids and cerebral aneurysm risk from a Mendelian randomization study
Yu W, Mei Y, Li C, Lu Z, Chen X, Yu H, Chen X, Huang Q, Li Z, Xiao D, Zhou L, Wang Z
medRxiv 2023.11.15.23298570; doi: https://doi.org/10.1101/2023.11.15.23298570
Serum uric acid and risk of diabetic neuropathy: a genetic correlation and mendelian randomization study
Zhang Y, Tang Z, Tong L, Wang Y, Li L
Front Endocrinol (Lausanne). 2023 Nov 15;14:1277984. doi: 10.3389/fendo.2023.1277984
The role of admixture in the rare variant contribution to inflammatory bowel disease
Astore C, Sharma S, Nagpal S; NIDDK IBD Genetics Consortium; Cutler DJ, Rioux JD, Cho JH, McGovern DPB, Brant SR, Kugathasan S, Jordan IK, Gibson G
Genome Med. 2023 Nov 15;15(1):97. doi: 10.1186/s13073-023-01244-w
Beverage consumption and diabetic retinopathy: a two-sample Mendelian randomization study
Xufang Sun, Suyun Rao, Ziqing Zhou, Ruohong Wang, Yuhe Tan
Researchsquare, 15 November 2023, doi: 10.21203/rs.3.rs-3505911/v1
Association of coffee and caffeine consumption with risk and prognosis of endometrial cancer and its subgroups: a Mendelian randomization
Chen Z, Liu C, Wu J, Kong F
Front Nutr. 2023 Nov 14;10:1291355. doi: 10.3389/fnut.2023.1291355
Rheumatoid arthritis increases the risk of malignant neoplasm of bone and articular cartilage: a two-sample bidirectional mendelian randomization study
Yang M, Su Y, Xu K, Xie J, Wen P, Liu L, Yang Z, Xu P
Arthritis Res Ther. 2023 Nov 13;25(1):219. doi: 10.1186/s13075-023-03205-5
Brain-Wide Mendelian Randomization Study of Anxiety Disorders and Symptoms
Zanoaga MD, Friligkou E, He J, Pathak GA, Koller D, Cabrera-Mendoza B, Stein MB, Polimanti R
Biol Psychiatry. 2023 Nov 13:S0006-3223(23)01718-3. doi: 10.1016/j.biopsych.2023.11.006
Genome-wide association study analysis of disease severity in Acne reveals novel biological insights
Du Z, Iyyanki T, Lessard S, Chao M, FinnGen, Asbrand C, Nassar D, Klinger K, de Rinaldis E, Khader S, Chatelain C
medRxiv 2023.11.13.23298473; doi: https://doi.org/10.1101/2023.11.13.23298473
Exploring Causal Cytokines and Potential Regulatory Genes in Bronchiectasis: Findings from Mendelian randomization
Wan-Zhe Liao, Hao-Bin Zhou, Zi-Kai Lin, Zhi-Yi Zhou, Xu-Guang Guo
Researchsquare, 13 November 2023, doi:10.21203/rs.3.rs-3588224/v1
Does gestational diabetes mellitus increase the risk of cardiovascular disease? A Mendelian randomization study
Liang W, Sun FF
J Endocrinol Invest. 2023 Nov 12. doi: 10.1007/s40618-023-02233-x
Unraveling shared risk factors for diabetic foot ulcer: a comprehensive Mendelian randomization analysis
Yin K, Qiao T, Zhang Y, Liu J, Wang Y, Qi F, Deng J, Zhao C, Xu Y, Cao Y
BMJ Open Diabetes Res Care. 2023 Nov;11(6):e003523. doi: 10.1136/bmjdrc-2023-003523
Proteome-wide Mendelian randomization highlights AIF1 and HLA-DQA2 as targets for primary sclerosing cholangitis
Chen L, Zhao Y, Li M, Lv G
Hepatol Int. 2023 Nov 11. doi: 10.1007/s12072-023-10608-8
Protective effect of uridine on atrial fibrillation: a Mendelian randomisation study
Xu X, Zhang X, Cheng S, Li Q, Chen C, Ouyang M
Sci Rep. 2023 Nov 10;13(1):19639. doi: 10.1038/s41598-023-47025-8
Assessment of the relationship between thyroid function and panic disorder: A mendelian randomization study
Sijie Yu, Chongkai Shen, Junpeng Zhu
Researchsquare, 10 November 2023, doi: 10.21203/rs.3.rs-3577312/v1
Causal effect between gut microbiota and pancreatic cancer: a two-sample Mendelian randomization study
Jiang Z, Mou Y, Wang H, Li L, Jin T, Wang H, Liu M, Jin W
BMC Cancer. 2023 Nov 10;23(1):1091. doi: 10.1186/s12885-023-11493-y
The genetics of falling susceptibility and identification of causal risk factors
Smith MC, O'Loughlin J, Karageorgiou V, Casanova F, Williams GKR, Hilton M, Tyrrell
Sci Rep. 2023 Nov 9;13(1):19493. doi: 10.1038/s41598-023-44566-w
Causal association between tea intake and acute cerebrovascular events: a multivariate Mendelian randomized study in European populations
Deng X, Zhu J, Liang J, Chang W, Lv X, Lai R, Gong L, Cai Y, Liu S
J Nutr. 2023 Nov 9:S0022-3166(23)72714-4. doi: 10.1016/j.tjnut.2023.10.027
Milo2.0 unlocks population genetic analyses of cell state abundance using a count-based mixed model
Alice K, Marioni JC, Morgan MD
bioRxiv 2023.11.08.566176; doi: https://doi.org/10.1101/2023.11.08.566176
No causal effect of genetically determined circulating homocysteine levels on psoriasis in the European population: evidence from a Mendelian randomization study
Chen C, Liu S, Liu J, Zheng Z, Zheng Y, Lin Z, Liu Y
Front Immunol. 2023 Nov 8;14:1288632. doi: 10.3389/fimmu.2023.1288632
Roles of gut microbiota in atrial fibrillation: insights from Mendelian randomization analysis and genetic data from over 430,000 cohort study participants
Dai H, Hou T, Wang Q, Hou Y, Zhu Z, Zhu Y, Zhao Z, Li M, Lin H, Wang S, Zheng R, Xu Y, Lu J, Wang T, Ning G, Wang W, Zheng J, Bi Y, Xu M
Cardiovasc Diabetol. 2023 Nov 8;22(1):306. doi: 10.1186/s12933-023-02045-6.
Reassessment of casual association between body mass index and site-specific solid cancers: A comprehensive Mendelian randomization study
Jianxiong Lai, Yuanhui Xu, Jian Li
Researchsquare, 07 November 2023, doi:10.21203/rs.3.rs-3552788/v1
Causal relationship between gut microbiota and myasthenia gravis: a bidirectional mendelian randomization study
Su T, Yin X, Ren J, Lang Y, Zhang W, Cui L
Cell Biosci. 2023 Nov 7;13(1):204. doi: 10.1186/s13578-023-01163-8
Causal associations between modifiable risk factors and intervertebral disc degeneration
Guo W, Li BL, Zhao JY, Li XM, Wang LF
Spine J. 2023 Nov 6:S1529-9430(23)03487-3. doi: 10.1016/j.spinee.2023.10.021
Effects of gut microbiota on prostatic cancer: a two-sample Mendelian randomization study
Xie Q, Hu B
Front Microbiol. 2023 Nov 6;14:1250369. doi: 10.3389/fmicb.2023.1250369
Circadian Rhythm and the Risk of Cardiovascular Diseases: Genetic Evidence
Yan L, Chen J, Li F, Chen Y, Mei Z, Chen L
Aging Dis. 2023 Nov 5. doi: 10.14336/AD.2023.1018
Therapeutic targets for endometriosis: genome-wide Mendelian randomization and colocalization analyses
Zeng P, Lu L, Zhang H, Li Y, Tan S, Yu T, Zhou H
Gene. 2023 Nov 4:147970. doi: 10.1016/j.gene.2023.147970
Impact of blood pressure and antihypertensive drug classes on intracranial aneurysm: a Mendelian randomization study
Zeng Y, Guo R, Cao S, Yang H
J Stroke Cerebrovasc Dis. 2023 Nov;32(11):107355. doi: 10.1016/j.jstrokecerebrovasdis.2023.107355