På den här sidan listar vi alla vetenskapliga publikationer som har använt data från FinnGen-studien.

2024

September

Immune Cell Influence on Diffuse Large B-Cell Lymphoma: A Mendelian Randomization Analysis
He H, Zhong J, Li Q, Deng C, Yuan X, Zhang K, Nie L, Cai N.
bioRxiv 2024.09.05.611435; doi: https://doi.org/10.1101/2024.09.05.611435
Exploring the causal link among statin drugs and the osteoarthritis risk based on Mendelian randomization research
Chen W, Sun Z, Xiong X, Tan H, Hu J, Liu C, Chen C.
Front Genet. 2024 Sep 4;15:1390387. doi: 10.3389/fgene.2024.1390387.
Causation between the gut microbiota and inguinal hernia: a two-sample double-sided Mendelian randomization study
Wu C, Zhu Y, Xi H.
Sci Rep. 2024 Sep 4;14(1):20526. doi: 10.1038/s41598-024-71253-1.
Causal effects of obstructive sleep apnea on chronic kidney disease and renal function: a bidirectional Mendelian randomization study
Hou Y, Li Y, Xiao Z, Wang Z.
Front Neurol. 2024 Sep 4;15:1323928. doi: 10.3389/fneur.2024.1323928.
Leveraging pleiotropy identifies common-variant associations with selective IgA deficiency
Willis TW, Gkrania-Klotsas E, Wareham NJ, McKinney EF, Lyons PA, Smith KGC, Wallace C.
Clin Immunol. 2024 Nov;268:110356. doi: 10.1016/j.clim.2024.110356.
Causal Relationship Between Autoimmune Arthritis and Temporomandibular Disorders
Li XF, Cai JW, Hu YY, Niu YM.
Int Dent J. 2024 Sep 3:S0020-6539(24)01417-5. doi: 10.1016/j.identj.2024.08.006.
Metabolic Characteristics of Gut Microbiota and Insomnia: Evidence from a Mendelian Randomization Analysis
Xie F, Feng Z, Xu B.
Nutrients. 2024 Sep 2;16(17):2943. doi: 10.3390/nu16172943.
The causal association between gut microbiota and postpartum depression: a two-sample Mendelian randomization study
Jin W, Li B, Wang L, Zhu L, Chai S, Hou R.
Front Microbiol. 2024 Sep 2;15:1415237. doi: 10.3389/fmicb.2024.1415237.
Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset
von Berg J, McArdle PF, Häppölä P, Haessler J, Kooperberg C, Lemmens R, Pezzini A, Thijs V, Pulit SL, Kittner SJ, Mitchell BD, de Ridder J, van der Laan SW.
Front Genet. 2024 Sep 2;15:1392061. doi: 10.3389/fgene.2024.1392061.
Lipids, lipid-lowering drugs and lateral epicondylitis of the humerus: a drug-targeted Mendelian randomization study
Liu MM, Chen X, Bao XH, Huang BH.
Front Genet. 2024 Sep 2;15:1437712. doi: 10.3389/fgene.2024.1437712.
Effects of rheumatoid arthritis on ventricular structure and function: a Mendelian randomization study
Hao Liu, Di Luo, Wei Yan, Jinsong Li, Dezhi Yan
Researchsquare, 02 September 2024, doi: 10.21203/rs.3.rs-4713343/v1
Association of maternal gut microbial metabolites with gestational diabetes mellitus: evidence from an original case-control study, meta-analysis, and Mendelian randomization
Yao M, Xiao Y, Sun Y, Zhang B, Ding Y, Ma Q, Liang F, Yang Z, Ge W, Liu S, Xin L, Yin J, Zhu X.
Eur J Clin Nutr. 2024 Sep 2. doi: 10.1038/s41430-024-01502-z.
Causal associations between gut microbiota and premature rupture of membranes: a two-sample Mendelian randomization study
Zhang L, Li Q, Huang J, Zou Q, Zou H, Zhang X, Su Y, Li C.
Front Immunol. 2024 Sep 2;15:1440232. doi: 10.3389/fimmu.2024.1440232.
Polygenic risk score portability for common diseases across genetically diverse populations
Moreno-Grau S, Vernekar M, Lopez-Pineda A, Mas-Montserrat D, Barrabés M, Quinto-Cortés CD, Moatamed B, Lee MTM, Yu Z, Numakura K, Matsuda Y, Wall JD, Ioannidis AG, Katsanis N, Takano T, Bustamante CD.
Hum Genomics. 2024 Sep 2;18(1):93. doi: 10.1186/s40246-024-00664-y.
Association of gut microbiota with acute kidney injury: a two-sample Mendelian randomisation and case-control study
Liu Y, Zhang J, Zhou Y, Xin Y, Li H, Huang P, Li N, Zhou Y, Luan F, Li Y, Zhang Q, Yuan M, Liu Y, Liu L, Song Y, Shen L, Xiao Y, Liu Y, Peng Y, Wang X, Yu K, Zhao M, Wang C.
Benef Microbes. 2024 Sep 2:1-15. doi: 10.1163/18762891-bja00032.
Whole -genome survival analysis of 144 286 people from the UK Biobank identifies novel loci associated with blood pressure
Saluja S, Darlay R, Lennon R, Keavney BD, Cordell HJ.
J Hypertens. 2024 Sep 1;42(9):1647-1652. doi: 10.1097/HJH.0000000000003801.
Risk of Parkinson's disease and depression severity in different populations: A two-sample Mendelian randomization analysis
Qin Y, Li J, Quan W, Song J, Xu J, Chen J.
Brain Behav. 2024 Sep;14(9):e3642. doi: 10.1002/brb3.3642.

Augusti

Parkinson's disease and the risk of gastrointestinal cancers: a two-sample Mendelian randomization study
Liu Z, Cui L.
J Gastrointest Oncol. 2024 Aug 31;15(4):1475-1486. doi: 10.21037/jgo-24-106.
Elucidating the causal nexus between antibody-mediated immunity and autoimmune diseases: Insights from bidirectional mendelian randomization, gene expression profiling, and drug sensitivity analysis
Chen J, Wei C, Huang S, Wu S, He R, Chen T, Qin X, Wei W, Qin B, Wu S, Zhu J, Huang C, Feng S, Zhou Z, Zhang B, Xue J, Mo S, Zhou C, Qin Y, Zhan X, Liu C.
Int Immunopharmacol. 2024 Aug 30;142(Pt A):113027. doi: 10.1016/j.intimp.2024.113027.
Specific blood metabolite associations with Gout: a Mendelian randomization study
Zeng H, Lai J, Liu Z, Liu W, Zhang Y.
Eur J Clin Nutr. 2024 Aug 30. doi: 10.1038/s41430-024-01497-7.
Health condition and socioeconomic status mediate the causal effect of reproductive traits on nonalcoholic fatty liver disease: evidence from Mendelian randomization study
Wang Q, Wang L, Hao R, Zhang L, Wang W, Xia L.
Front Endocrinol (Lausanne). 2024 Aug 30;15:1419964. doi: 10.3389/fendo.2024.1419964.
Causal Effects of Kidney Function and Chronic Kidney Disease on Alzheimer's Disease by Analyzing Large-Scale Genome-Wide Association Study Datasets
Zhao H, Yuan H, Wang E.
J Alzheimers Dis. 2024 Aug 30. doi: 10.3233/JAD-240807.
Mitochondrial dysfunction and onset of type 2 diabetes along with its complications: a multi-omics Mendelian randomization and colocalization study
Li Y, Miao Y, Feng Q, Zhu W, Chen Y, Kang Q, Wang Z, Lu F, Zhang Q.
Front Endocrinol (Lausanne). 2024 Aug 30;15:1401531. doi: 10.3389/fendo.2024.1401531.
Causal relationships between gut microbiota, plasma metabolites, and HIV infection: insights from Mendelian randomization and mediation analysis
Hu J, Hu J, Han D.
Virol J. 2024 Aug 30;21(1):204. doi: 10.1186/s12985-024-02480-1.
A study on the causal relationship between the gut microbiome and herpes zoster using Mendelian randomization
Meng Z, Wang T, Liao Y, Li X.
Front Med (Lausanne). 2024 Aug 30;11:1442750. doi: 10.3389/fmed.2024.1442750.
Genetic analysis from multiple cohorts implies causality between 2200 druggable genes, telomere length, and leukemia
Yun Z, Liu Z, Shen Y, Sun Z, Zhao H, Du X, Lv L, Zhang Y, Hou L.
Comput Biol Med. 2024 Aug 30;181:109064. doi: 10.1016/j.compbiomed.2024.109064.
Postpartum depression and autoimmune disease: a bidirectional Mendelian randomization study
Yu W, Su B, Wang C, Xia Q, Sun Y.
Front Psychiatry. 2024 Aug 29;15:1425623. doi: 10.3389/fpsyt.2024.1425623.
Exploring causal correlations between plasma proteins and peripheral neuropathy: a Mendelian randomization
Song M, Chen F, Li X, Chen L.
Front Neurol. 2024 Aug 29;15:1431669. doi: 10.3389/fneur.2024.1431669.
Primary biliary cholangitis has causal effects on systemic rheumatic diseases: a Mendelian randomization study
Zhang HP, Zhou Z, Chen K, Xiong LF, Wu J, Jin L.
BMC Gastroenterol. 2024 Aug 29;24(1):294. doi: 10.1186/s12876-024-03319-3.
Repurposing antihypertensive drugs for pain disorders: a drug-target mendelian randomization study
Du K, Li A, Zhang CY, Li SM, Chen P.
Front Pharmacol. 2024 Aug 29;15:1448319. doi: 10.3389/fphar.2024.1448319.
Obesity mediates the relationship between depression and infertility: insights from the NHANES 2013-2018 cross-sectional study and a Mendelian randomization study
Xu T, Zhuang Y, Cao H, Yang J.
Front Endocrinol (Lausanne). 2024 Aug 29;15:1465105. doi: 10.3389/fendo.2024.1465105.
Exploring causal effects of sarcopenia on risk and progression of Parkinson disease by Mendelian randomization
Wang T, Geng J, Zeng X, Han R, Huh YE, Peng J.
NPJ Parkinsons Dis. 2024 Aug 28;10(1):164. doi: 10.1038/s41531-024-00782-3.
The Causal Relationship Between Physical Activity and Skin Cancer Risk: An Univariable Mendelian Randomization Study
Fu X, Zeng F, Li L, Liu G, Zhong Q, Chen S.
Clin Cosmet Investig Dermatol. 2024 Aug 28;17:1963-1972. doi: 10.2147/CCID.S472443.
Multivariable Mendelian Randomization Analysis Reveals the Protective Effect of Restless Legs Syndrome against Lower Limb Venous Diseases and Pulmonary Embolism
Zhang R-Y, Wen C, Geng R-L, Su J-H, Liu X-H, Lai Z-Y, Tao E-X, Li F-J.
medRxiv 2024.08.27.24312632; doi: https://doi.org/10.1101/2024.08.27.24312632
Inflammatory factors and risk of lung adenocarcinoma: a Mendelian randomization study mediated by blood metabolites
Ding Z, Chen J, Li B, Ji X.
Front Endocrinol (Lausanne). 2024 Aug 27;15:1446863. doi: 10.3389/fendo.2024.1446863.
Quantifying variant contributions in cystic kidney disease using national-scale whole genome sequencing
Sadeghi-Alavijeh O, Chan MM, Doctor GT, Voinescu CD, Stuckey A, Kousathanas A, Ho AT, Stanescu HC, Bockenhauer D, Sandford RN, Levine AP, Gale DP.
J Clin Invest. 2024 Aug 27:e181467. doi: 10.1172/JCI181467.
Associations Between Gut Microbiota and Alcohol Abuse: A Mendelian Randomisation and Bioinformatics Study
Wang X, Pan L, Gu J, Gu L, Lou M, Liu Y.
J Mol Neurosci. 2024 Aug 26;74(3):80. doi: 10.1007/s12031-024-02259-7.
Therapeutically targeting the classical complement pathway with antisense oligonucleotides in Alzheimer’s disease
Wang Y, Wu T, Gogineni A, Tsai M-C, Kielpinski L, Mahajan A, Pandey S, Schachner L, Tran JC, Wu C, Schauer S, Biever A, Boesen S, Li M, Munk A, Meilandt WJ, Elstrott J, Easton A, Gylling HM, Hanson JE.
bioRxiv 2024.08.23.609240; doi: https://doi.org/10.1101/2024.08.23.609240
Causal associations of obstructive sleep apnea with Chronic Respiratory Diseases: a Mendelian Randomization study
Hong PY, Liu D, Liu A, Su X, Zhang XB, Zeng YM.
BMC Pulm Med. 2024 Aug 26;24(1):409. doi: 10.1186/s12890-024-03228-x.
Primary immunodeficiency-related genes and varicella-zoster virus reactivation syndrome: a Mendelian randomization study
Wang H, Chen G, Gong Q, Wu J, Chen P.
Front Immunol. 2024 Aug 26;15:1403429. doi: 10.3389/fimmu.2024.1403429.
Elucidating the relationship between coffee consumption and obsessive-compulsive disorder: A Mendelian randomization study
Jiawei Wang, Minyan Feng, Zhiguo Li, Weifan Li
Researchsquare, 26 August 2024, doi: 10.21203/rs.3.rs-4724718/v1
A Two-Sample Mendelian Randomization Study of Neuroticism and Sleep Bruxism
Strausz T, Strausz S, Jones SE, Palotie T, Lobbezoo F, Ahlberg J, Ollila HM.
J Dent Res. 2024 Aug 26:220345241264749. doi: 10.1177/00220345241264749.
Causal Effect of Tobacco Exposure on Acute Respiratory Distress Syndrome: A Mendelian Randomization Study
Yunfeng Wang, Zhihui Cheng, Dongwei Xu, Kan Shen, Jun Li, Shenghua Yan, Maofeng Zhou, Yingchao Qi, Hua Yu, Hui Ni, Lijun Liao, Yuling Li, Xingqi Deng
Researchsquare, 26 August 2024, doi: 10.21203/rs.3.rs-4806401/v1
Investigating the causal relationship between major depressive disorder and benign prostatic hyperplasia: a bidirectional Mendelian randomisation study
Zheng G, Xiao S, Cheng Y, Huang J, Luo C, Peng L, Zeng T.
Psychogeriatrics. 2024 Aug 26. doi: 10.1111/psyg.13180.
Metabolic factors are not the direct mediators of the association between type 2 diabetes and osteoporosis
Yang Q, Wang X, Liu Y, Liu J, Zhu D.
Front Endocrinol (Lausanne). 2024 Jul 25;15:1404747. doi: 10.3389/fendo.2024.1404747.
Causal associations of osteoporosis with stroke: a bidirectional Mendelian randomization study
Fan Z, Zhao J, Chen J, Hu W, Ma J, Ma X.
Osteoporos Int. 2024 Aug 24. doi: 10.1007/s00198-024-07235-w.
Causal relationships between gut microbiome and obstructive sleep apnea: a bi-directional Mendelian randomization
Liu L, He G, Yu R, Lin B, Lin L, Wei R, Zhu Z, Xu Y.
Front Microbiol. 2024 Aug 23;15:1410624. doi: 10.3389/fmicb.2024.1410624.
Causal association between blood leukocyte counts and vascular dementia: a two-sample bidirectional Mendelian randomization study
Liu S, Zhang C, Zhang Y, Wu Z, Wu P, Tian S, Zhang M, Lang L, Li L, Wang R, Liu H, Zhang J, Mao X, Li S.
Sci Rep. 2024 Aug 23;14(1):19582. doi: 10.1038/s41598-024-70446-y.
Relationship of Hypothyroidism with Alopecia Areata and Androgenetic Alopecia: Insights from a Two-Sample Mendelian Randomization Study
Zhang G, Huang X, Li H, Gong H, Zhou Y, Liu F.
Clin Cosmet Investig Dermatol. 2024 Aug 22;17:1865-1874. doi: 10.2147/CCID.S474168.
Causal relationship between genetically predicted antibody-Mediated Immune Responses and female infertility
Mo W, Zhang J, Peng X, Wang Y.
J Reprod Immunol. 2024 Aug 22;166:104319. doi: 10.1016/j.jri.2024.104319.