Research highlights

This section showcases recent research findings enabled by FinnGen data and the Finnish biobank participants. Below you can find several examples of how FinnGen is helping to increase our understanding of the genetic drivers of human diseases, pinpointing possible therapeutic targets.
Study Identifies Severe Side Effects of the Most Effective Schizophrenia Medication
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A recent Finnish study found that pneumonia and severe gastrointestinal complications are more common with the most effective schizophrenia medication than previously thought. These side effects…
Six genetic regions associated with normal pressure hydrocephalus identified
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A new study by the University of Eastern Finland and partners identified new genetic variants associated with normal pressure hydrocephalus (NPH). Published in Neurology, the study is the first large…
New insights into genetic triggers of X chromosome loss illuminate links to autoimmunity and cancer
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An international team of researchers has uncovered genetic factors that predispose women to a genetic phenomenon where some cells lose one of their two X chromosomes.
Inherited predisposition for higher muscle strength may protect against common morbidities
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A study conducted at the Faculty of Sport and Health Sciences at the University of Jyväskylä showed that a genetic predisposition for higher muscle strength predicts a longer lifespan and a lower…
New gene defect discovery helps to unlock the mystery of severe infectious mononucleosis
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A new hereditary disease was found in Finns, which manifests as severe infectious mononucleosis. The genetic defect can lead to the treatment of many different diseases.
One in ten women would benefit from earlier breast cancer screening, a genetic study shows
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Recent results from researchers at the University of Helsinki indicate that genetic risk information can help tailor and target breast cancer screening more effectively to the women who would benefit…
Immune genetics plays a significant role in lung cancer risk
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Genes regulating the immune response influence an individual's risk of lung cancer, according to a study published in the world's leading scientific journal. Having less diverse HLA…
Genetic study clarifies the link between birth weight and adult morbidity
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A unique Finnish study has investigated the link between growth conditions in the womb and cardiovascular disease in adulthood. The results highlight the importance of shared genetic factors between…
Genetic information can improve colorectal cancer screening
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Hereditary risk of colorectal cancer should be assessed in a more comprehensive way, shows a study led by researchers at the University of Helsinki, Finland. Using comprehensive genetic information,…
A Leap Forward in Women's Health: Unlocking Genetic Clues to Gestational Diabetes
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The largest genetic study of gestational diabetes to date has led to a discovery of nine novel genetic regions linked to this severe and common pregnancy complication. The results shed light on…