Intrahepatic cholestasis of pregnancy (ICP) is the most common liver condition that occurs during pregnancy and is characterised by a disruption in the normal flow of bile from the liver. A new international study has identified a strong link between the genetic susceptibility to ICP and the body’s ability to regulate bile acids and metabolise lipids and cholesterol. The findings open up new avenues for research into maternal health and pregnancy-related liver diseases.

An international research team has identified dozens of new genetic risk factors linked to lumbar spinal stenosis, a common degenerative condition of the lower spine. The study, led by researchers at the University of Oulu, provides new insight into the biological mechanisms behind one of the most frequent causes of mobility problems in older adults.

An international collaboration of genetic researchers has identified more than 90 genetic regions associated with the risk of Alzheimer’s disease and related dementias. The large-scale meta-analysis reveals new biological insights into the disease, highlighting the important roles of immune processes, beta-amyloid and tau biology, and lipid metabolism.

FinnGen at ESHG 2026: discover our latest science through talks and posters across the programme!

We are pleased to announce the release of FinnGen Data Freeze 13!

A doctoral dissertation by Veera Timonen shows how combining artificial intelligence, imaging and multi-omics data can advance understanding of human biology at scale, while also demonstrating a practical path to studying the function of disease-associated genetic variants.

A major genetic risk factor for delirium has been identified in a landmark study that analysed the DNA of more than one million people worldwide.

Cardiac arrhythmias such as atrial fibrillation can pose a significant health risk or even lead to sudden death. At the same time, the prevention and treatment of these conditions is very difficult. In a study of genetic and medical data sets from over 1 million individuals, the digital health team led by Dr. Henrike Heyne and Julian Wanner at the Hasso Plattner Institute investigated a gene variant called T220I in a sodium channel in the heart, which provides important new insights.

Depression in young adulthood has a stronger hereditary component and is associated with a higher risk of suicide attempts than depression that begins later in life, according to a new study published in Nature Genetics by researchers at Karolinska Institutet, among others.

A new Nordic study was the first to investigate the impact of genetic and social factors in shaping educational pathways. The study showed that genes have a small but clearly detectable influence on the choice of field of study.