Research highlights

This section showcases recent research findings enabled by FinnGen data and the Finnish biobank participants. Below you can find several examples of how FinnGen is helping to increase our understanding of the genetic drivers of human diseases, pinpointing possible therapeutic targets.
The power of a genetic isolate: Hundreds of novel genetic discoveries from the FinnGen study
A map of Finland with chromosomes surrounding it, and human figures representing all stages of human lifespan.
New results from the FinnGen research consortium demonstrate the undeniable benefits of Finnish health research environment for genomic research. Among the wealth of novel genetic discoveries are…
Beyond Mendel: FinnGen study sheds new light on well-established theories of genetic inheritance
A drawing of a family with two children, showing the classical inheritance model, with question marks on top.
A large-scale biobank-based study performed in Finland has discovered several new disease genes as well as new insights on how known genetic factors affect disease. The study highlights an…
A significant genetic defect linked to female infertility identified in Finland
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A study has discovered a genetic defect that affects the maturation of oocytes, leading to infertility in women. This discovery provides new insights into the genetic causes of infertility and may…
Researchers discover dozens of new genes associated with disc herniations
An abstract human figure with a red glowing sphere at the lower back.
Lumbar disc herniation is one of the most common structural changes in the lower back and the most common cause of radiating pain, or sciatica, in the leg.
Study Identifies Severe Side Effects of the Most Effective Schizophrenia Medication
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A recent Finnish study found that pneumonia and severe gastrointestinal complications are more common with the most effective schizophrenia medication than previously thought. These side effects…
Six genetic regions associated with normal pressure hydrocephalus identified
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A new study by the University of Eastern Finland and partners identified new genetic variants associated with normal pressure hydrocephalus (NPH). Published in Neurology, the study is the first large…
New insights into genetic triggers of X chromosome loss illuminate links to autoimmunity and cancer
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An international team of researchers has uncovered genetic factors that predispose women to a genetic phenomenon where some cells lose one of their two X chromosomes.
Inherited predisposition for higher muscle strength may protect against common morbidities
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A study conducted at the Faculty of Sport and Health Sciences at the University of Jyväskylä showed that a genetic predisposition for higher muscle strength predicts a longer lifespan and a lower…
New gene defect discovery helps to unlock the mystery of severe infectious mononucleosis
Two scientists, holding a DNA molecule in their hands.
A new hereditary disease was found in Finns, which manifests as severe infectious mononucleosis. The genetic defect can lead to the treatment of many different diseases.
One in ten women would benefit from earlier breast cancer screening, a genetic study shows
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Recent results from researchers at the University of Helsinki indicate that genetic risk information can help tailor and target breast cancer screening more effectively to the women who would benefit…