Below you will find all the published and preprint scientific papers using FinnGen data.

2024

February

Understanding the educational inequalities in suicide attempts and their mediators: a Mendelian randomisation study
Zhu J, Liu H, Gao R, Ding L, Wang J, Yang Y, Zhou D, Li Y.
Gen Psychiatr. 2024 Feb 19;37(1):e101369. doi: 10.1136/gpsych-2023-101369.
No causal association between atopic dermatitis and COVID-19 outcomes: A Mendelian randomization study
Jin C, Li Y.
Skin Res Technol. 2024 Feb;30(2):e13619. doi: 10.1111/srt.13619.
Unraveling COVID-19 relationship with anxiety disorders and symptoms using genome-wide data
Asgel Z, Kouakou MR, Koller D, Pathak GA, Cabrera-Mendoza B, Polimanti R.
J Affect Disord. 2024 Feb 19;352:333-341. doi: 10.1016/j.jad.2024.02.061.
No evidence of a causal relationship between miscarriage and 25-hydroxyvitamin D: a Mendelian randomization study
Zhang F, Huang J, Zhang G, Dai M, Yin T, Huang C, Liu J, Zhang Y.
Hum Reprod Open. 2024 Feb 19;2024(2):hoae011. doi: 10.1093/hropen/hoae011.
Genetic influences on circulating retinol and its relationship to human health
Reay WR, Kiltschewskij DJ, Di Biase MA, Gerring ZF, Kundu K, Surendran P, Greco LA, Clarke ED, Collins CE, Mondul AM, Albanes D, Cairns MJ.
Nat Commun. 2024 Feb 19;15(1):1490. doi: 10.1038/s41467-024-45779-x.
Exploring the interplay of gut microbiota, inflammation, and LDL-cholesterol: a multiomics Mendelian randomization analysis of their causal relationship in acute pancreatitis and non-alcoholic fatty liver disease
Yan C, Bao J, Jin J.
J Transl Med. 2024 Feb 19;22(1):179. doi: 10.1186/s12967-024-04996-0.
Gene deletions in complement factor H related protein gene locus and kidney transplantation
Markkinen S, Helanterä I, Lauronen J, Lempinen M, Partanen J, Hyvärinen K.
Kidney Int Rep. 2022 Sep 6;7(11):2484-2494. doi: 10.1016/j.ekir.2022.08.032
Assessing the Role of Cortisol in Anxiety, Major Depression, and Neuroticism: A Mendelian Randomization Study Using SERPINA6/ SERPINA1 Variants
Chan II, Wu AMS.
Biol Psychiatry Glob Open Sci. 2024 Feb 18;4(3):100294. doi: 10.1016/j.bpsgos.2024.100294.
Associations between gut microbiota and three prostate diseases: a bidirectional two-sample Mendelian randomization study
Liu X, Dong Q.
Sci Rep. 2024 Feb 18;14(1):4019. doi: 10.1038/s41598-024-54293-5.
Causal relationship between hypothyroidism and temporomandibular disorders: evidence from complementary genetic methods
Chen X, Xu J, Cheng Z, Wang Q, Zhao Z, Jiang Q.
BMC Oral Health. 2024 Feb 17;24(1):247. doi: 10.1186/s12903-024-03999-z.
Mineral Metabolism and Polycystic Ovary Syndrome and Metabolic Risk Factors: A Mendelian Randomization Study
Shen J, Xu L, Wu X, Ding Y.
Reprod Sci. 2024 Feb 16. doi: 10.1007/s43032-024-01476-0.
Serum urate is associated with an increased risk of inflammatory bowel disease: A bidirectional Mendelian randomization study
Zhang S, Fang X, Kang L, Sui XY, Liu M, Luo YJ, Fu S, Li ZS, Zhao SB, Bai Y.
World J Clin Cases. 2024 Feb 16;12(5):891-902. doi: 10.12998/wjcc.v12.i5.891.
Circulating micronutrient levels and their association with sepsis susceptibility and severity: a Mendelian randomization study
Wei Z, Liu Y, Mei X, Zhong J, Huang F.
Front Genet. 2024 Feb 16;15:1353118. doi: 10.3389/fgene.2024.1353118.
Effect of viral hepatitis on type 2 diabetes: A Mendelian randomization study
Yu YF, Hu G, Tong KK, Yang XY, Wu JY, Yu R.
World J Diabetes. 2024 Feb 15;15(2):220-231. doi: 10.4239/wjd.v15.i2.220.
The causal effect of air pollution on the risk of essential hypertension: a Mendelian randomization study
Xia Z, Liu Y, Liu C, Dai Z, Liang X, Zhang N, Wu W, Wen J, Zhang H.
Front Public Health. 2024 Feb 15;12:1247149. doi: 10.3389/fpubh.2024.1247149.
Causality Assessment Between Idiopathic Inflammatory Myopathies and Lung Cancer: A Bidirectional 2-Sample Mendelian Randomization
Li H, Xu Y, Guo Q, Zhang T, Zhou S, Wang Q, Tian Y, Cheng Y, Guo C.
J Clin Rheumatol. 2024 Feb 14. doi: 10.1097/RHU.0000000000002075.
The Relationship Between Systemic Lupus Erythematosus and Osteoporosis Based on Different Ethnic Groups: a Two-Sample Mendelian Randomization Analysis
Shi YK, Yuan KH, Fu ZM, Hu RR, Wang H.
Calcif Tissue Int. 2024 Feb 14. doi: 10.1007/s00223-024-01190-8.
Assessing the causal relationship between psychiatric disorders and obstructive sleep apnea: a bidirectional Mendelian randomization
Mi C, Hou A, Liu Y, Qi X, Teng J.
Front Psychiatry. 2024 Feb 14;15:1351216. doi: 10.3389/fpsyt.2024.1351216.
Associations between gut microbiota and adverse neurodevelopmental outcomes in preterm infants: a two-sample Mendelian randomization study
Wang Y, Cheng T, Cui Y, Qu D, Peng X, Yang L, Xiao X.
Front Neurosci. 2024 Feb 14;18:1344125. doi: 10.3389/fnins.2024.1344125.
Genomics-Microbiome Based Assessment of Bidirectional Causality Between Gut Microbiota and Psoriasis
Gao Q, Liu JH, Ma WY, Cheng ZL, Hao PS, Luo NN.
Clin Cosmet Investig Dermatol. 2024 Feb 13;17:435-445. doi: 10.2147/CCID.S450227.
Evaluation of bidirectional causal association between cardiovascular diseases and pneumonia: A Mendelian randomization study
Zhang Y, Liu H, Dai Y, Ye F, Luo W, Tu S, Chen W, Kong S, He Y, Tan N, Zhang Z, He P, Liu Y.
Eur J Prev Cardiol. 2024 Feb 13:zwae060. doi: 10.1093/eurjpc/zwae060.
Dietary factors and the risk of atopic dermatitis: A Mendelian randomization study
Che Y, Yuan J, Wang Q, Liu M, Tang D, Chen M, Xiao X, Pang Y, Chen S, Han W, Xiao Z, Zeng J, Guo J.
Br J Nutr. 2024 Feb 12:1-31. doi: 10.1017/S0007114524000436.
Disentangling the link between maternal influences on birth weight and disease risk in 36,211 genotyped mother-child pairs
Leinonen JT; FinnGen; Pirinen M, Tukiainen T.
Commun Biol. 2024 Feb 12;7(1):175. doi: 10.1038/s42003-024-05872-9.
Causal association of smoking, blood lipids, and bladder cancer: Insights from a multivariable and mediation mendelian randomization investigation
Wei H, Cheng X, Wang G, Li Z, Du W, Ju L, Shan D, Yu M, Fang Y, Qian K, Zhang Y, Xiao Y, Wang X.
J Cancer. 2024 Feb 12;15(7):1929-1939. doi: 10.7150/jca.92306.
Genetically proxied PCSK9 inhibition is associated with reduced psoriatic arthritis risk
Li J, Li J, Lin C, Zhou J, Wang J, Wang F, Li H, Zhou Z.
Inflamm Res. 2024 Feb 11. doi: 10.1007/s00011-024-01850-3.
Gut microbiota and risk for the diverticular disease of intestine
Wenhui He, Youzhen Yu, Na Luo, Shangqing Xu, Wenwen Yang, Fanfan Li, Hui Zhu, Hongying Jin, Yimei Zhang, Xiaoli Ma, Minjie Ma
Researchsquare, 11 January 2024, https://doi.org/10.21203/rs.3.rs-3834819/v1
Genetic link between primary biliary cholangitis and connective tissue diseases in European populations: A two-sample Mendelian randomization study
Liu Z, Shao Y, Duan X.
PLoS One. 2024 Feb 9;19(2):e0298225. doi: 10.1371/journal.pone.0298225.
Bacteroidaceae, Bacteroides, and Veillonella: emerging protectors against Graves' disease
Liu S, Li F, Cai Y, Ren L, Sun L, Gang X, Wang G.
Front Cell Infect Microbiol. 2024 Feb 9;14:1288222. doi: 10.3389/fcimb.2024.1288222.
Association between human blood metabolome and the risk of pre-eclampsia
Ding Y, Yao M, Liu J, Fu W, Zhu X, He Y, Ma Q, Zhang C, Yin J.
Hypertens Res. 2024 Feb 8. doi: 10.1038/s41440-024-01586-x.
Assessing causality between chronic obstructive pulmonary disease with depression: A bidirectional Mendelian randomization study
Liu A, Hong PY, Su B, Wu JH, Chen ZY.
J Affect Disord. 2024 Feb 8:S0165-0327(24)00331-8. doi: 10.1016/j.jad.2024.02.022.
Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis
Tang J, Mo S, Fan L, Fu S, Liu X.
Front Immunol. 2024 Feb 8;15:1284466. doi: 10.3389/fimmu.2024.1284466.
Genetic Analysis of Obstructive Sleep Apnea and Its Relationship with Severe COVID-19
Strausz S, Agafonova E, Tiullinen V, Kiiskinen T, Broberg M, Ruotsalainen SE, Koskela J, Bachour A, Sofer T, Gottlieb DJ, Palotie A, Palotie T, Ripatti S, Ollila HM.
Ann Am Thorac Soc. 2024 Feb 8. doi: 10.1513/AnnalsATS.202303-215OC.
Association between hypothyroidism subtypes and major depression: A two-sample Mendelian randomization study
Zhou H, Zhu H, Wang J, Gao X, Jiang C.
J Affect Disord. 2024 Feb 8:S0165-0327(24)00315-X. doi: 10.1016/j.jad.2024.02.006.
Association between Daytime Napping and Incident Arrhythmias: A Prospective Cohort Study and a Mendelian Randomization Analysis
Gao QY, Zhang HF, Gao JW, Cai JW, Chen Q, You S, Chen ZT, Guo DC, Li ST, Hao QY, Liu PM, Wang JF, Chen YX.
Heart Rhythm. 2024 Feb 7:S1547-5271(24)00114-0. doi: 10.1016/j.hrthm.2024.02.004.
Causal associations between gut microbiota, metabolites and asthma: a two-sample Mendelian randomization study
Li J, Zhang C, Tang J, He M, He C, Pu G, Liu L, Sun J.
BMC Pulm Med. 2024 Feb 7;24(1):72. doi: 10.1186/s12890-024-02898-x.
Inflammatory cytokines and oral lichen planus: a Mendelian randomization study
Chen X, Zhang S, Wu X, Lei Y, Lei B, Zhao Z.
Front Immunol. 2024 Feb 7;15:1332317. doi: 10.3389/fimmu.2024.1332317.
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders
Lu Z, Li X, Qi Y, Li B, Chen L.
J Transl Med. 2024 Feb 6;22(1):138. doi: 10.1186/s12967-024-04941-1.
Association between green tea intake and digestive system cancer risk in European and East Asian populations: a Mendelian randomization study
Nie D, He X, Zheng H, Deng D, He F, Li R, Ni X, Li S, Xu F.
Eur J Nutr. 2024 Feb 6. doi: 10.1007/s00394-023-03312-8.
Causal relationship between gut microbiota and autoimmune thyroiditis: A mendelian study
Xiong Y, Zhu X, Luo Q.
Heliyon. 2024 Feb 6;10(3):e25652. doi: 10.1016/j.heliyon.2024.e25652.
Identification of the VLDLR locus associated with giant cell arteritis and the possible causal role of low-density lipoprotein cholesterol in its pathogenesis
Iwasaki T, Watanabe R, Zhang H, Hashimoto M, Morinobu A, Matsuda F.
Rheumatology (Oxford). 2024 Feb 6:keae075. doi: 10.1093/rheumatology/keae075.
The Role of the Gut Microbiome and Microbial Dysbiosis in Common Skin Diseases
Ryguła I, Pikiewicz W, Grabarek BO, Wójcik M, Kaminiów K.
Int J Mol Sci. 2024 Feb 6;25(4):1984. doi: 10.3390/ijms25041984.
Unraveling the mystery: a Mendelian randomized exploration of gut microbiota and different types of obesity
Liu S, Li F, Cai Y, Ren L, Sun L, Gang X, Wang G.
Front Cell Infect Microbiol. 2024 Feb 5;14:1352109. doi: 10.3389/fcimb.2024.1352109.
Causal relationships of physical activity and leisure sedentary behaviors with COPD: A Mendelian randomization study
Gao Y, Li C, Li J, Li L.
Arch Gerontol Geriatr. 2024 Feb 5;121:105364. doi: 10.1016/j.archger.2024.105364.
Associations between ADHD and risk of six psychiatric disorders: a Mendelian randomization study
Guo Y, Li J, Hu R, Luo H, Zhang Z, Tan J, Luo Q.
BMC Psychiatry. 2024 Feb 5;24(1):99. doi: 10.1186/s12888-024-05548-y.
Identifying novel proteins for suicide attempt by integrating proteomes from brain and blood with genome-wide association data
Zhao H, Liu Y, Zhang X, Liao Y, Zhang H, Han X, Guo L, Fan B, Wang W, Lu C.
Neuropsychopharmacology. 2024 Feb 5. doi: 10.1038/s41386-024-01807-4.
Effects of menstrual disorders and dysmenorrhea on cardiovascular disease: a Mendelian randomization study
Lai S, Jin Q, Wang D, Li T, Wang X.
Front Endocrinol (Lausanne). 2024 Feb 5;15:1302312. doi: 10.3389/fendo.2024.1302312.
Hypothyroidism is a causal determinant of age-related cataract risk in European population: a Mendelian randomization study
Liu S, Sun Q, Gu Q, Bao Y, Wang W, Qin X, Yuan X.
Front Endocrinol (Lausanne). 2024 Feb 5;15:1254793. doi: 10.3389/fendo.2024.1254793.
Evidence for Genetic Causal Relationships Between Multiple Immune-Mediated Inflammatory Diseases and Age-Related Macular Degeneration: A Univariable and Multivariable Mendelian Randomization Study
Sha F, Li H, Zhang L, Liang F.
Ophthalmol Ther. 2024 Feb 5. doi: 10.1007/s40123-024-00895-1.
Revisiting an old relationship: the causal associations of the ApoB/ApoA1 ratio with cardiometabolic diseases and relative risk factors-a mendelian randomization analysis
Fu C, Liu D, Liu Q, Wang X, Ma X, Pan H, Feng S, Sun Z, Qiao W, Yang M, Gao S, Ding H, Huang X, Hou J.
Cardiovasc Diabetol. 2024 Feb 3;23(1):51. doi: 10.1186/s12933-024-02140-2.
Bidirectional two-sample Mendelian randomization analysis identifies causal associations between cardiovascular diseases and frozen shoulder
Lu W, Pu B, Wang S, Li M, An Y, Lian J, Wang Y.
J Orthop Surg Res. 2024 Feb 3;19(1):116. doi: 10.1186/s13018-024-04600-7.