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Integrating multi-omics and mendelian randomization identifies therapeutic targets for Lichen Sclerosus: A druggable genome-wide study

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:36
  • Read more about Integrating multi-omics and mendelian randomization identifies therapeutic targets for Lichen Sclerosus: A druggable genome-wide study

CFHR5 promotes colorectal cancer by upregulating COX4I2 to inhibit ferroptosis

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:35
  • Read more about CFHR5 promotes colorectal cancer by upregulating COX4I2 to inhibit ferroptosis

Genetic evidence for causality between thyroid function and endometriosis: A bidirectional 2-sample Mendelian randomization study

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:34
  • Read more about Genetic evidence for causality between thyroid function and endometriosis: A bidirectional 2-sample Mendelian randomization study

Mapping the genetically predicted associations between lower-extremity muscle traits and spinal diseases

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:33
  • Read more about Mapping the genetically predicted associations between lower-extremity muscle traits and spinal diseases

Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:32
  • Read more about Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms

Proton Pump Inhibitor Target Genes and Asthma Susceptibility: A Mendelian Randomization Study with Identification of IL-2 as a Potential Mediator

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:31
  • Read more about Proton Pump Inhibitor Target Genes and Asthma Susceptibility: A Mendelian Randomization Study with Identification of IL-2 as a Potential Mediator

Integrative transcriptomic, experimental, and Mendelian randomization evidence implicates CREB1 in chronic sleep deprivation-induced anxiety-like phenotypes

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:31
  • Read more about Integrative transcriptomic, experimental, and Mendelian randomization evidence implicates CREB1 in chronic sleep deprivation-induced anxiety-like phenotypes

Plasticizer-related toxicogenomic signatures in gestational diabetes: Mendelian randomization, placental single-cell transcriptomics and trophoblast validation

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:30
  • Read more about Plasticizer-related toxicogenomic signatures in gestational diabetes: Mendelian randomization, placental single-cell transcriptomics and trophoblast validation

Psychological Well-Being, Neuroticism, and the Risk of Benign Paroxysmal Positional Vertigo: A Triangulation Study

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:29
  • Read more about Psychological Well-Being, Neuroticism, and the Risk of Benign Paroxysmal Positional Vertigo: A Triangulation Study

Hyperthyroidism Is Genetically Associated With Reduced Risk of Parkinson's Disease: A Mendelian Randomization Analysis

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Submitted by Anna Hakala on Tue, 07/14/2026 - 12:28
  • Read more about Hyperthyroidism Is Genetically Associated With Reduced Risk of Parkinson's Disease: A Mendelian Randomization Analysis

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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