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Mendelian randomization combined with real-world study reveals that Streptococcus anginosus exacerbates dietary triglyceride metabolism disorders in obese mice

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:46
  • Read more about Mendelian randomization combined with real-world study reveals that Streptococcus anginosus exacerbates dietary triglyceride metabolism disorders in obese mice

Mediation Mendelian randomization study of plasma proteomics reveals the causal relationship and potential mechanisms between iron and colorectal adenocarcinoma

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:45
  • Read more about Mediation Mendelian randomization study of plasma proteomics reveals the causal relationship and potential mechanisms between iron and colorectal adenocarcinoma

Synergistic blood-based diagnostic value of AP3B1 and BMPR2 in Parkinson’s disease

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:38
  • Read more about Synergistic blood-based diagnostic value of AP3B1 and BMPR2 in Parkinson’s disease

Uncovering Novel Susceptible Genes and Therapeutic Targets of Prostate Cancer: a Multi-omics Study Integrating Summary-based Mendelian Randomization Analysis and Molecular Docking

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:37
  • Read more about Uncovering Novel Susceptible Genes and Therapeutic Targets of Prostate Cancer: a Multi-omics Study Integrating Summary-based Mendelian Randomization Analysis and Molecular Docking

First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:36
  • Read more about First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia

Integrated multi-omics analysis reveals AKR1C1 as a key mediator of intervertebral disc degeneration: protecting against ferroptosis via PI3K/AKT signaling

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:35
  • Read more about Integrated multi-omics analysis reveals AKR1C1 as a key mediator of intervertebral disc degeneration: protecting against ferroptosis via PI3K/AKT signaling

Cyclic cytokines mediated the effect of immune cells on meningioma: a two-step, mediation mendelian randomization study

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:34
  • Read more about Cyclic cytokines mediated the effect of immune cells on meningioma: a two-step, mediation mendelian randomization study

Exploration of the mechanism of intestinal flora–mediated immune modulation in the pathogenesis of gout

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:31
  • Read more about Exploration of the mechanism of intestinal flora–mediated immune modulation in the pathogenesis of gout

Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:30
  • Read more about Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology

Investigating the potential causal link between BPA and ovarian carcinogenesis: a network toxicology and mendelian randomization study on the CTRC/PRDX1/SKP1 pathway

Submitted by Anna Hakala on Wed, 11/19/2025 - 14:29
  • Read more about Investigating the potential causal link between BPA and ovarian carcinogenesis: a network toxicology and mendelian randomization study on the CTRC/PRDX1/SKP1 pathway

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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