Tältä sivulta löydät kaikki FinnGen-aineistoa hyödyntäneet julkaisut ja preprint-artikkelit.
2023

September

Gut microbiota and hypertensive disorders in pregnancy: evidence from the Mendelian randomization study
Wu X, Li Q, Lin D, Cai J, Huang H, Tan H.
Aging (Albany NY). 2023 Sep 11;15. doi: 10.18632/aging.205019.
Causal relationships between circulating inflammatory factors and IgA vasculitis: a bidirectional Mendelian randomization study
Qin J, Zhang L, Ke B, Liu T, Kong C, Jin C.
Front Immunol. 2023 Sep 11;14:1248325. doi: 10.3389/fimmu.2023.1248325.
Causal Relationships between Obesity and Thyroid Function and Thyroid Disease: A Two-Sample Mendelian Randomization Study
Ziqi Zhang, Yuqing Sun, Jieyu Niu, Peipei Zhou, Xiqiao Zhou, Jiangyi Yu
Researchsquare, 11 September 2023, doi: 10.21203/rs.3.rs-3324638/v1
Causal associations of 25-hydroxyvitamin D with functional gastrointestinal disorders: a two-sample Mendelian randomization study
Xu S, Luo Q, He J, Chen X, Li S, Bai Y.
Genes Nutr. 2023 Sep 11;18(1):14. doi: 10.1186/s12263-023-00734-1.
The causal relationship between thyroid function, autoimune thyroid dysfunction and lung cancer: a mendelian randomization study
Wang X, Liu X, Li Y, Tang M, Meng X, Chai Y, Zhang L, Zhang H
BMC Pulm Med. 2023 Sep 11;23(1):338. doi: 10.1186/s12890-023-02588-0.
Identification of potential drug targets for rheumatoid arthritis from genetic insights: a Mendelian randomization study
Cao Y, Yang Y, Hu Q, Wei G
J Transl Med. 2023 Sep 11;21(1):616. doi: 10.1186/s12967-023-04474-z
The causal role of insomnia in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies
Chi Wang, Jing Jiang, Chengyong Liu, Xiaoqiu Wang, Qingyun Wan, Xiya Yuan, Kai Liu, Wenzhong Wu
Researchsquare, 11 September 2023, doi: 10.21203/rs.3.rs-3239691/v1
Changes in the gut microbial profile during long-term androgen deprivation therapy for prostate cancer
Wang L
Prostate Cancer Prostatic Dis. 2023 Sep 11. doi: 10.1038/s41391-023-00723-w
Detecting potential causal relationship between inflammatory bowel disease and rosacea using bi-directional Mendelian randomization
Li M, He SX, He YX, Hu XH, Zhou Z
Sci Rep. 2023 Sep 9;13(1):14910. doi: 10.1038/s41598-023-42073-6
Correlation of diet and micronutrients with microvascular complications of diabetes mellitus: A Mendelian randomization analysis
Shengdan Pu, Yuxin Xu, Xiaotong Sun, Xuewei Tong, Yitong Zhang, Xinyuan Gao
Researchsquare, 08 September 2023, doi:10.21203/rs.3.rs-3301717/v1
Long-term outcomes of offspring from multiple gestations: a two-sample Mendelian randomization study on multi-system diseases using UK Biobank and FinnGen databases
Jiang Y, Du Y, Su R, Zhou X, Wei L, Zhang J, Zhu S, Zhang H, Fang C, Chen Y, Gao P, Zhang L, Wang S, Yu J, He M, Ding W, Feng L.
J Transl Med. 2023 Sep 8;21(1):608. doi: 10.1186/s12967-023-04423-w.
Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria
McSweeney SM, Saklatvala J, Rispoli R, Ganier C, Woszczek G, Thomas L, Hveem K, Løset M, Dand N, Tziotzios C, Simpson M, McGrath JA.
J Allergy Clin Immunol. 2023 Sep 8:S0091-6749(23)01117-X. doi: 10.1016/j.jaci.2023.08.033.
Causality of Diabetic Nephropathy and Age-related Macular Degeneration: A Mendelian Randomization Study.
Chen X, Chen L, Lin Y, Li G.
Gene. 2023 Sep 7:147787. doi: 10.1016/j.gene.2023.147787.
Smoking, alcohol consumption and risk of Dupuytren’s disease: a Mendelian randomization study
Wang Z, Wang Z, Yan Z, Xu Z, Gao A
BMC Med Genomics. 2023 Sep 7;16(1):212. doi: 10.1186/s12920-023-01650-4
The Genetic Causal Association between Educational Attainment and Risk of 12 Common Musculoskeletal Disorders: A Two-Sample Mendelian Randomization
Sun K, Ming Y, Wu Y, Zeng Y, Xu J, Wu L, Li M, Shen B.
Orthop Surg. 2023 Sep 7. doi: 10.1111/os.13821.
A second update on mapping the human genetic architecture of COVID-19
The COVID-19 Host Genetics Initiative
Nature 621, E7–E26 (2023). https://doi.org/10.1038/s41586-023-06355-3
Serum albumin and risk of incident diabetes and diabetic microvascular complications in the UK biobank cohort
Cai YW, Zhang HF, Gao JW, Cai ZX, Cai JW, Gao QY, Chen ZT, Liao GH, Zeng CR, Chen N, Liu PM, Wang JF, Chen YX.
Diabetes Metab. 2023 Sep 5:101472. doi: 10.1016/j.diabet.2023.101472.
Genetically predicted body mass index and maternal outcomes of pregnancy: A two-sample Mendelian randomisation study.
Ardissino M, Geddes-Barton M, Banerjee A.
BJOG. 2023 Sep 5. doi: 10.1111/1471-0528.17650.
Birth weight, childhood obesity, adulthood obesity and body composition, and gastrointestinal diseases: a Mendelian randomization study
Yuan S, Ruan X, Sun Y, Fu T, Zhao J, Deng M, Chen J, Li X, Larsson SC.
Obesity (Silver Spring). 2023 Oct;31(10):2603-2614. doi: 10.1002/oby.23857.
Causality assessment of circulating Vitamin D level on venous thromboembolism: A Mendelian randomization study
Zhang X, Sun W, Li N, Jian X, Geng T, Wu L, Wang Y, Wang B, Zheng D
Nutr Metab Cardiovasc Dis. 2023 Sep;33(9):1800-1807. doi: 10.1016/j.numecd.2023.05.019
Causal associations between type 1 diabetes mellitus and cardiovascular diseases: A Mendelian randomization study
Liu Z, Wang H, Yang Z, Lu Y, Zou C.
Cardiovasc Diabetol. 2023 Sep 2;22(1):236. doi: 10.1186/s12933-023-01974-6.
Mendelian randomization study shows a causal effect of asthma on chronic obstructive pulmonary disease risk
Li Y, Wang W, Zhou D, Lu Q, Li L, Zhang B.
PLoS One. 2023 Sep 1;18(9):e0291102. doi: 10.1371/journal.pone.0291102.

August

Mendelian Randomization analyses between body mass index and atrioventricular block: underweight is a risky state
Yuchen Ying, Dihui Cai, Jiangfang Lian
Researchsquare, 31 August 2023, doi: 10.21203/rs.3.rs-3234637/v1
Causal relationship between dietary intake and diabetic retinopathy: a two-sample Mendelian randomization study
Yuxin Cheng, Xuanyi Chen, Guangyu Zhu, Yue Sun, Shichun Luo, Yujie Liu, Na Li, Xuejing lu
Researchsquare, 31 August 2023, doi: 10.21203/rs.3.rs-3258626/v1
Mendelian randomization analysis reveals causality of inflammatory bowel disease on risks of Henoch-Schönlein purpura and immune thrombocytopenia
Li H, Xin Q, Hong L, Hu Y, Lin L, Guo M, Jiang H, He C, Wang S, Li M.
Dig Liver Dis. 2023 Aug 31:S1590-8658(23)00856-3. doi: 10.1016/j.dld.2023.08.044.
Association between 23 drugs and Parkinson's disease: A two-sample Mendelian randomization study
Xie Z, Zhou H, Qiu Z, Fan Z, Yang W, Zhang J, Wang Y, Ye Y.
Brain Behav. 2023 Aug 31:e3225. doi: 10.1002/brb3.3225.
GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture
International League Against Epilepsy Consortium on Complex Epilepsies.
Nat Genet. 2023 Sep;55(9):1471-1482. doi: 10.1038/s41588-023-01485-w.
Vitamin D Status, Vitamin D Receptor Polymorphisms, and the Risk of Incident Rosacea: Insights from Mendelian Randomization and Cohort Study in the UK Biobank
Mao R, Zhou G, Jing D, Liu H, Shen M, Li J
Nutrients. 2023 Aug 30;15(17):3803. doi: 10.3390/nu15173803
A polygenic risk score for Alzheimer's disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S
Sofer T, Kurniansyah N, Granot-Hershkovitz E, Goodman MO, Tarraf W, Broce I, Lipton RB, Daviglus M, Lamar M, Wassertheil-Smoller S, Cai J, DeCarli CS, Gonzalez HM, Fornage M.
Alzheimers Res Ther. 2023 Aug 30;15(1):146. doi: 10.1186/s13195-023-01298-3.
Obesity and risk for respiratory diseases: a Mendelian randomization study
Yang W, Yang Y, Guo Y, Guo J, Ma M, Han B.
Front Endocrinol (Lausanne). 2023 Aug 29;14:1197730. doi: 10.3389/fendo.2023.1197730.
Evaluating the role of amino acids in type 2 diabetes risk: a Mendelian randomization study
Mo J, He B, Wong T, Liang Y, Luo S, Lo K, Louie J, Yeung SLA
medRxiv 2023.08.27.23294702; doi:https://doi.org/10.1101/2023.08.27.23294702
Univariable and multivariable mendelian randomization study revealed the modifiable risk factors of urolithiasis
Fang H, Deng J, Chen Q, Chen D, Diao P, Peng L, Lai B, Zeng Y, Han Y.
PLoS One. 2023 Aug 25;18(8):e0290389. doi: 10.1371/journal.pone.0290389.
No evidence for a genetic causal effect of breast cancer on venous thromboembolism: a mendelian randomization study.
Qin Q, Pan Y, Wang L.
J Thromb Thrombolysis. 2023 Aug 24. doi: 10.1007/s11239-023-02871-1.
Genome-wide meta-analysis identifies novel loci and improves disease prediction of age-related macular degeneration
He W, Han X, Ong JS, Wu Y, Hewitt AW, Mackey DA, Gharahkhani P, MacGregor S.
Ophthalmology. 2023 Aug 25:S0161-6420(23)00622-X. doi: 10.1016/j.ophtha.2023.08.023.
No genetic causal association between dental caries and Alzheimer's disease: a bidirectional two-sample Mendelian randomization analysis.
Liao Q, Li SZ, Tian FF, Huang K, Bi FF.
PeerJ. 2023 Aug 23;11:e15936. doi: 10.7717/peerj.15936.
Mendelian randomization analysis revealed a gut microbiota-mammary axis in breast cancer
Zhang S, Zhang W, Ren H, Xue R, Wang Z, Wang Z, Lv Q.
Front Microbiol. 2023 Aug 23;14:1193725. doi: 10.3389/fmicb.2023.1193725.
Dietary factors and the risk of urolithiasis: A Mendelian randomization study
Xing Li, Lei Zhang, Yanjun Li, Tefei Lu, Libin Zhou
Researchsquare, 23 August 2023, doi: 10.21203/rs.3.rs-3153700/v1
Plasma proteins and onset of type 2 diabetes and diabetic complications: Proteome-wide Mendelian randomization and colocalization analyses
Yuan S, Xu F, Li X, Chen J, Zheng J, Mantzoros CS, Larsson SC.
Cell Rep Med. 2023 Aug 22:101174. doi: 10.1016/j.xcrm.2023.101174.
The relationship between sex hormone-binding protein and non-alcoholic fatty liver disease using Mendelian randomisation
Dong J, Liu C, Lu J, Wang L, Xie S, Ji L, Lu B.
Eur J Clin Invest. 2023 Aug 22:e14082. doi: 10.1111/eci.14082
Genetically Predicted Vegetable Intake and Cardiovascular Diseases and Risk Factors: An Investigation with Mendelian Randomization
Feng Q, Grant AJ, Yang Q, Burgess S, Bešević J, Conroy M, Omiyale W, Sun Y, Allen N, Lacey B
Nutrients. 2023 Aug 22;15(17):3682. doi: 10.3390/nu15173682
Causal relationship of genetically predicted circulating micronutrients levels with the risk of kidney stone disease: a Mendelian randomization study
Yang J, Wu W, Amier Y, Li X, Wan W, Yu X.
Front Nutr. 2023 Aug 21;10:1132597. doi: 10.3389/fnut.2023.1132597
An atlas of associations between 14 micronutrients and 22 cancer outcomes: Mendelian randomization analyses
Kim JY, Song M, Kim MS, Natarajan P, Do R, Myung W, Won HH.
BMC Med. 2023 Aug 21;21(1):316. doi: 10.1186/s12916-023-03018-y.
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study
Pham TT, Nimptsch K, Papadimitriou N, Aleksandrova K, Jenab M, Gunter MJ, Le Marchand L, Li L, Lynch BM, Castellví-Bel S, Phipps AI, Schmit SL, Brenner H, Ogino S, Giovannucci E, Pischon T.
J Cancer Res Clin Oncol. 2023 Aug 21. doi: 10.1007/s00432-023-05193-0.
Investigation of the causal relationship between Interleukin-6 signaling and gastrointestinal tract cancers: A Mendelian randomization study
Yang Z, Guo L, Sun Y, Huang Y, Li J, Lin Y, Zhang X, Wu D, Luo Y.
Dig Liver Dis. 2023 Aug 21:S1590-8658(23)00855-1. doi: 10.1016/j.dld.2023.08.040.
Transient ischemic attack and coronary artery disease: a two-sample Mendelian randomization analysis.
Qi X, Wang S, Qiu L, Chen X, Huang Q, Ouyang K, Chen Y.
Front Cardiovasc Med. 2023 Aug 21;10:1192664. doi: 10.3389/fcvm.2023.1192664.
Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT Study
Tynkkynen NP, Törmäkangas T, Palviainen T, Hyvärinen M, Klevjer M, Joensuu L, Kujala U, Kaprio J, Bye A, Sillanpää E
Eur J Epidemiol. 2023 Sep;38(9):995-1008. doi: 10.1007/s10654-023-01029-w
Lipids, lipid-modifying drug target genes and migraine: a Mendelian randomization study
Bi Y, Zhu Y, Tang S, Huang Y
J Headache Pain. 2023 Aug 18;24(1):112. doi: 10.1186/s10194-023-01633-x.
Causal effects of Sjögren's syndrome on cancer risk: A Mendelian Randomization Study
Hao Cheng, Jin-Hong Xu, Chen-Chen Wu, Zhi-Xia Wang, Xue-Lian Xu
Researchsquare, 18 August 2023, doi: 10.21203/rs.3.rs-3259871/v1
Environmental and occupational risk factors for COPD and its prevalence among miners worldwide: a Mendelian randomization and meta-analysis study
Liu Z, Pan H, Liu B, Li L, Yang H, Shen T.
Environ Sci Pollut Res Int. 2023 Aug 18. doi: 10.1007/s11356-023-29269-z.
Cheese consumption and risk of diabetic retinopathies: A Mendelian Randomization study
Lin Z, Hu D, Jiang J
medRxiv 2023.08.18.23294288; doi: https://doi.org/10.1101/2023.08.18.23294288