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Bidirectional Mendelian Randomization Suggests Causal Effects of 731 Immunophenotypes on Vitiligo Pathogenesis

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Submitted by Anna Hakala on Wed, 05/20/2026 - 13:07
  • Read more about Bidirectional Mendelian Randomization Suggests Causal Effects of 731 Immunophenotypes on Vitiligo Pathogenesis

DNA Methylation-Mediated Regulation of TAGLN2 Expression Promotes Pulmonary Arterial Hypertension

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Submitted by Anna Hakala on Wed, 05/20/2026 - 13:06
  • Read more about DNA Methylation-Mediated Regulation of TAGLN2 Expression Promotes Pulmonary Arterial Hypertension

Global, regional, and national burden of non-rheumatic calcific aortic valve disease from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021 and Mendelian randomization analysis

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:05
  • Read more about Global, regional, and national burden of non-rheumatic calcific aortic valve disease from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021 and Mendelian randomization analysis

Identification of Potential Oxidative Stress-Related Causal Genes for Calculus of Kidney and Ureter: A Multi-Omics Mendelian Randomization Analysis

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:04
  • Read more about Identification of Potential Oxidative Stress-Related Causal Genes for Calculus of Kidney and Ureter: A Multi-Omics Mendelian Randomization Analysis

Causal effects of life-course obesity on sleep apnoea: a Mendelian randomization study

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:03
  • Read more about Causal effects of life-course obesity on sleep apnoea: a Mendelian randomization study

Integrating immune-cell transcriptomic data with Mendelian randomisation reveals novel causal genes for type 2 diabetes and its complications

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:02
  • Read more about Integrating immune-cell transcriptomic data with Mendelian randomisation reveals novel causal genes for type 2 diabetes and its complications

Exploring Mitochondrial Genetic Features in Intervertebral Disc Degeneration through Multi-Omics Integration Analyses

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:02
  • Read more about Exploring Mitochondrial Genetic Features in Intervertebral Disc Degeneration through Multi-Omics Integration Analyses

Mendelian randomization analysis links HLA-DR+ CD14- CD16+ monocytes to CCL19-driven ankylosing spondylitis risk

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:01
  • Read more about Mendelian randomization analysis links HLA-DR+ CD14- CD16+ monocytes to CCL19-driven ankylosing spondylitis risk

Sedentary behavior, physical activity, psychological well-being, and gynecologic and obstetric disorders: A multivariable Mendelian randomization and mediation analysis

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Submitted by Anna Hakala on Wed, 05/20/2026 - 12:00
  • Read more about Sedentary behavior, physical activity, psychological well-being, and gynecologic and obstetric disorders: A multivariable Mendelian randomization and mediation analysis

Potential therapeutic targets for multisite chronic pain: A proteome-wide Mendelian randomization study

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Submitted by Anna Hakala on Wed, 05/20/2026 - 11:15
  • Read more about Potential therapeutic targets for multisite chronic pain: A proteome-wide Mendelian randomization study

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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