Extensive genetic study performed in Finland has provided further insights into the genetic risk factors that influence susceptibility to upper respiratory tract infections. The results help to understand individual differences in infection susceptibility and reveal common risk factors underlying several types of infections.
A study led by the University of Helsinki has identified more than 300 gene regions associated with the use of cholesterol drugs, antihypertensives or antidiabetic drugs. Genomic regions linked to drug use also helped identify new cardiovascular disease risk genes.
The FinnGen research team has identified 27 hereditary risk factors for otosclerosis, a disease that disrupts the function of bones in the middle ear and causes hearing loss. Some of the identified genetic variants are specific to the Finnish population.
According to a large Finnish biobank study, normal variation in baseline testosterone levels in adulthood is an individual characteristic among others and should not be considered the main determinant of appearance, behaviour and disease susceptibility.