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Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the pathogenicity spectrum of monogenic diabetes genes

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 10:24
  • Read more about Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the pathogenicity spectrum of monogenic diabetes genes

Multi-biobank Mendelian randomization analyses identify opposing pathways in plasma low-density lipoprotein-cholesterol lowering and gallstone disease

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 10:19
  • Read more about Multi-biobank Mendelian randomization analyses identify opposing pathways in plasma low-density lipoprotein-cholesterol lowering and gallstone disease

Fast and scalable ensemble learning method for versatile polygenic risk prediction

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 10:15
  • Read more about Fast and scalable ensemble learning method for versatile polygenic risk prediction

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 10:12
  • Read more about Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

Genetically Informed Study Highlights Income-Independent Effect of Schizophrenia Liability on Mental and Physical Health

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 10:04
  • Read more about Genetically Informed Study Highlights Income-Independent Effect of Schizophrenia Liability on Mental and Physical Health

The impact of common and rare genetic variants on bradyarrhythmia development

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 09:56
  • Read more about The impact of common and rare genetic variants on bradyarrhythmia development

Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 09:46
  • Read more about Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

The causal associations between cancers and cardiovascular diseases: a two-sample bidirectional Mendelian randomization analysis

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 09:26
  • Read more about The causal associations between cancers and cardiovascular diseases: a two-sample bidirectional Mendelian randomization analysis

A machine-learning method for biobank-scale genetic prediction of blood group antigens

Submitted by Viola Mäkelä on Mon, 10/02/2023 - 09:16
  • Read more about A machine-learning method for biobank-scale genetic prediction of blood group antigens

Lipid Metabolism Traits Mediate the Effect of Psoriasis on Myocardial Infarction Risk: A Two-Step Mendelian Randomization Study

Submitted by Viola Mäkelä on Thu, 09/28/2023 - 13:09
  • Read more about Lipid Metabolism Traits Mediate the Effect of Psoriasis on Myocardial Infarction Risk: A Two-Step Mendelian Randomization Study

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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