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Integrated metabolomics and genetic analyses reveal loss of protective docosahexaenoic acid as a key driver linking ultra-processed food to Crohn's disease risk

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:59
  • Read more about Integrated metabolomics and genetic analyses reveal loss of protective docosahexaenoic acid as a key driver linking ultra-processed food to Crohn's disease risk

Learning lifetime disease liability reveals and removes genetic confounding in electronic health records

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:58
  • Read more about Learning lifetime disease liability reveals and removes genetic confounding in electronic health records

Building The Human Genotype-Phenotype Map to Harness Pleiotropy and Refine Disease Mechanisms

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:57
  • Read more about Building The Human Genotype-Phenotype Map to Harness Pleiotropy and Refine Disease Mechanisms

Neuroticism as a protective factor for cardiomyopathy: A mediation Mendelian randomization study

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:44
  • Read more about Neuroticism as a protective factor for cardiomyopathy: A mediation Mendelian randomization study

Bidirectional causal associations between immune cell phenotypes and age-related macular degeneration subtypes: A mendelian randomization study

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:43
  • Read more about Bidirectional causal associations between immune cell phenotypes and age-related macular degeneration subtypes: A mendelian randomization study

Causal associations between abdominal obesity, dietary patterns, and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study with clinical validation

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:42
  • Read more about Causal associations between abdominal obesity, dietary patterns, and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study with clinical validation

Relationship between the microbiome and obesity-associated cancer risk using Mendelian randomisation

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:41
  • Read more about Relationship between the microbiome and obesity-associated cancer risk using Mendelian randomisation

Integration of TWAS with single-cell and spatial transcriptomics identifies TLR1 as a susceptibility gene and therapeutic target in the breast cancer tumor microenvironment

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:40
  • Read more about Integration of TWAS with single-cell and spatial transcriptomics identifies TLR1 as a susceptibility gene and therapeutic target in the breast cancer tumor microenvironment

Exploring the causal relationship between plasma proteins and obstructive sleep apnea: a study using genome-wide Mendelian randomization, single-cell RNA sequencing analysis, and network pharmacology

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:39
  • Read more about Exploring the causal relationship between plasma proteins and obstructive sleep apnea: a study using genome-wide Mendelian randomization, single-cell RNA sequencing analysis, and network pharmacology

Exploring Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus: MultiOmics Insights Through Mendelian Randomization

Submitted by Anna Hakala on Mon, 02/23/2026 - 13:38
  • Read more about Exploring Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus: MultiOmics Insights Through Mendelian Randomization

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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