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Novel Protein Biomarkers and Therapeutic Targets for Type 1 Diabetes and Its Complications: Insights from Summary-Data-Based Mendelian Randomization and Colocalization Analysis

Submitted by Frida Mäkelä on Mon, 08/05/2024 - 11:14
  • Read more about Novel Protein Biomarkers and Therapeutic Targets for Type 1 Diabetes and Its Complications: Insights from Summary-Data-Based Mendelian Randomization and Colocalization Analysis

No Evidence of an Association between Genetic Factors Affecting Response to Vitamin A Supplementation and Myopia: A Mendelian Randomization Study and Meta-Analysis

Submitted by Frida Mäkelä on Mon, 08/05/2024 - 11:11
  • Read more about No Evidence of an Association between Genetic Factors Affecting Response to Vitamin A Supplementation and Myopia: A Mendelian Randomization Study and Meta-Analysis

Gut Microbiota, Human Blood Metabolites, and Esophageal Cancer: A Mendelian Randomization Study

Submitted by Frida Mäkelä on Mon, 08/05/2024 - 11:08
  • Read more about Gut Microbiota, Human Blood Metabolites, and Esophageal Cancer: A Mendelian Randomization Study

Adenosine 5'-Monophosphate-to-Threonine Ratio Promotes Abdominal Aortic Aneurysms via Up-Regulation of HLA-DR on Natural Killer Cells: A Bidirectional Mendelian Randomized Analysis

Submitted by Frida Mäkelä on Mon, 08/05/2024 - 11:06
  • Read more about Adenosine 5'-Monophosphate-to-Threonine Ratio Promotes Abdominal Aortic Aneurysms via Up-Regulation of HLA-DR on Natural Killer Cells: A Bidirectional Mendelian Randomized Analysis

MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes

Submitted by Frida Mäkelä on Thu, 06/27/2024 - 10:33
  • Read more about MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes

Prescription glucocorticoid medication and iridocyclitis are associated with an increased risk of senile cataract occurrence: a Mendelian randomization study

Submitted by Frida Mäkelä on Thu, 06/27/2024 - 10:09
  • Read more about Prescription glucocorticoid medication and iridocyclitis are associated with an increased risk of senile cataract occurrence: a Mendelian randomization study

Two-sample Mendelian randomization analysis identifies a causal association between atopic dermatitis and impetigo

Submitted by Frida Mäkelä on Thu, 06/27/2024 - 10:01
  • Read more about Two-sample Mendelian randomization analysis identifies a causal association between atopic dermatitis and impetigo

Revealing the genetic complexity of hypothyroidism: integrating complementary association methods

Submitted by Frida Mäkelä on Thu, 06/27/2024 - 09:42
  • Read more about Revealing the genetic complexity of hypothyroidism: integrating complementary association methods

Leveraging pleiotropy identifies common-variant associations with selective IgA deficiency

Submitted by Frida Mäkelä on Tue, 06/25/2024 - 10:14
  • Read more about Leveraging pleiotropy identifies common-variant associations with selective IgA deficiency

Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits

Submitted by Frida Mäkelä on Mon, 06/24/2024 - 13:55
  • Read more about Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits

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The University of Helsinki is the organization responsible for the FinnGen research project. The Finnish consortium partners include all Finnish public biobanks and their background organisations, so the project covers the whole of Finland. All partners are listed on this page.

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