Within- and Between-Family Validation of Nine Polygenic Risk Scores Developed in 1.5 Million Individuals: Implications for IVF, Embryo Selection, and Reduction in Lifetime Disease Risk

Stephan Cordogan, D. Barry Starr, Nathan R. Treff, Jerry Lanchbury, Ellen Goldstein, Kian Sadeghi, Margit Burmeister, Lila Dayani, Peter Macdonald, J. Dianne Keen-Kim, Simon Fishel, Enrique Cervantes, Lasse Folkersen
medRxiv 2025.10.24.25338613; doi: https://doi.org/10.1101/2025.10.24.25338613
https://doi.org/10.1101/2025.10.24.25338613
Preprint
Feb 15, 2026
Consortium publication
No